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Rev Stomatol Chir Maxillofac. 1976 Jul-Aug;77(5):757-64.

[Drugs and drug combinations responsible for cutaneomucosal reactions].

Revue de stomatologie et de chirurgie maxillo-faciale

[Article in French]
H Dechy

PMID: 137515

Abstract

The drugs and drug combinations responsible for cutaneo-mucosal reactions are very numerous, which explains why this undesireable side effect is the most frequent of all. Multiple pathogenic mechanisms are described: immunoallergic with its different types of reactions, overdosage, idiosyncrasy, drug interactions, etc. The reactions of produced vary from the maculo-papular rash to definitive staining of the skin. A few specific cases have been analyzed: the allergic reactions with penicillins, the photo-toxicity of certain tetracyclines, licheniform eruptions with gold salts or lupus erythematosus with penicillamine. Centralization of pharmacological information is desireable in order to better understand these reactions.

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