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Nóvak EM, Werneck LC. Comprometimento neurologico por inseticidas. Estudo das manifestações cronicas em 13 casos [Neurologic involvement caused by insecticides. Study of chronic manifestations in 13 cases]. Arq Neuropsiquiatr. 1977;35(2):129-38doi: 10.1590/s0004-282x1977000200005.
Nóvak, E. M., & Werneck, L. C. (1977). Comprometimento neurologico por inseticidas. Estudo das manifestações cronicas em 13 casos [Neurologic involvement caused by insecticides. Study of chronic manifestations in 13 cases]. Arquivos de neuro-psiquiatria, 35(2), 129-38. https://doi.org/10.1590/s0004-282x1977000200005
Nóvak, E M, and Werneck, L C. "Comprometimento neurologico por inseticidas. Estudo das manifestações cronicas em 13 casos" [Neurologic involvement caused by insecticides. Study of chronic manifestations in 13 cases]. Arquivos de neuro-psiquiatria vol. 35,2 (1977): 129-38. doi: https://doi.org/10.1590/s0004-282x1977000200005
Nóvak EM, Werneck LC. Comprometimento neurologico por inseticidas. Estudo das manifestações cronicas em 13 casos [Neurologic involvement caused by insecticides. Study of chronic manifestations in 13 cases]. Arq Neuropsiquiatr. 1977 Jun;35(2):129-38. doi: 10.1590/s0004-282x1977000200005. Portuguese. PMID: 869736.
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Arq Neuropsiquiatr. 1977 Jun;35(2):129-38. doi: 10.1590/s0004-282x1977000200005.

[Neurologic involvement caused by insecticides. Study of chronic manifestations in 13 cases].

Arquivos de neuro-psiquiatria

[Article in Portuguese]
E M Nóvak, L C Werneck

PMID: 869736 DOI: 10.1590/s0004-282x1977000200005

Abstract

The clinical study of 13 patients with chronic neurological manifestation induced by insecticides (organophosphorades and organochlorades compounds) is reported. Twelve patients were male and farmers and one was a saleslady. The authors adopted five conditions for diagnosis: frequent contact with insecticides, synaptomatology directly related to the compounds exposition, clinical and laboratorial exclusion of others pathologies, quickly improvement of the symptoms when the patients were away from their original environment and high levels of insecticides in blood and urine determination. The clinical data was not uniform and the manifestation include pure motor neuropathy, mixed sensory-motor neuropathy, mielopathy and cranial nerves palsies. No relationship could be established between the insecticides (type, frequency of number of exposition) to the clinical picture. The insecticides determination was positive (moderated or elevated levels) in all patients and in 40% of controls (traces). Eletromyographic studies showed a neuropathic pattern in the majority of cases and reduced motor nerve conduction velocities. The authors believe that insecticides determination has a relative value and others criterion must be used in the diagnosis of chronic illness caused by insecticides. They think that others factors can be related with the symptomatology (hypersensibility, malnutrition, previous sensibilization or cumulative effect).

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