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Wilson P, Ramsden RT. Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels. Br Med J. 1977;1(6056):259-61doi: 10.1136/bmj.1.6056.259.
Wilson, P., & Ramsden, R. T. (1977). Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels. British medical journal, 1(6056), 259-61. https://doi.org/10.1136/bmj.1.6056.259
Wilson, P, and Ramsden, R T. "Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels." British medical journal vol. 1,6056 (1977): 259-61. doi: https://doi.org/10.1136/bmj.1.6056.259
Wilson P, Ramsden RT. Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels. Br Med J. 1977 Jan 29;1(6056):259-61. doi: 10.1136/bmj.1.6056.259. PMID: 837060; PMCID: PMC1604140.
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Br Med J. 1977 Jan 29;1(6056):259-61. doi: 10.1136/bmj.1.6056.259.

Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels.

British medical journal

P Wilson, R T Ramsden

PMID: 837060 PMCID: PMC1604140 DOI: 10.1136/bmj.1.6056.259
Free PMC Article

Abstract

Electrocochleography was performed on three patients to monitor the intravenous administration of tobramycin. When peak serum tobramycin levels exceeded 8-10 mug/ml an immediate dramatic reduction in cochlear output was observed, which recovered fully as serum levels fell. The patients had no auditory or vestibular symptoms either during or after treatment.

References

  1. Appl Microbiol. 1971 Dec;22(6):1147-51 - PubMed
  2. Arch Otolaryngol. 1976 Mar;102(3):154-9 - PubMed
  3. Am J Vet Res. 1971 Feb;32(2):357-9 - PubMed
  4. Life Sci. 1964 Oct;3:1151-5 - PubMed
  5. JAMA. 1964 Sep 14;189:817-22 - PubMed
  6. Arch Int Pharmacodyn Ther. 1963 Dec 1;146:549-60 - PubMed
  7. J Pharmacol Exp Ther. 1957 Aug;120(4):452-9 - PubMed
  8. Acta Otolaryngol. 1967 Jul;64(1):45-54 - PubMed
  9. Laryngoscope. 1967 Feb;77(2):159-70 - PubMed
  10. Acta Otolaryngol. 1975 Jan-Feb;79(1-2):24-32 - PubMed
  11. Appl Microbiol. 1972 Jan;23(1):4-7 - PubMed

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