Display options
Cite
Riess O, Winkelmann B, Epplen JT. Toward the complete genomic map and molecular pathology of human chromosome 4. Hum Genet. 1994;94(1):1-18doi: 10.1007/BF02272834.
Riess, O., Winkelmann, B., & Epplen, J. T. (1994). Toward the complete genomic map and molecular pathology of human chromosome 4. Human genetics, 94(1), 1-18. https://doi.org/10.1007/BF02272834
Riess, O, et al. "Toward the complete genomic map and molecular pathology of human chromosome 4." Human genetics vol. 94,1 (1994): 1-18. doi: https://doi.org/10.1007/BF02272834
Riess O, Winkelmann B, Epplen JT. Toward the complete genomic map and molecular pathology of human chromosome 4. Hum Genet. 1994 Jul;94(1):1-18. doi: 10.1007/BF02272834. PMID: 8034286.
Copy Download .nbib Format: NLM
Share it on

Hum Genet. 1994 Jul;94(1):1-18. doi: 10.1007/BF02272834.

Toward the complete genomic map and molecular pathology of human chromosome 4.

Human genetics

O Riess, B Winkelmann, J T Epplen

Affiliations

  1. Molekulare Humangenetik Ruhr-Universität, Bochum, Germany.

PMID: 8034286 DOI: 10.1007/BF02272834

Abstract

The identification of disease genes via molecular DNA cloning has revolutionized human genetics and medicine. Both the candidate gene approach and positional cloning have been used successfully. The defects causing Huntington's disease, facioscapulohumeral muscular dystrophy, piebaldism, Hurler/Scheie syndrome, one form of autosomal recessive retinitis pigmentosa, and a second locus for autosomal dominant polycystic kidney disease have recently been localized to chromosome 4. In addition to the rapid progress in the cloning of the 203-megabase chromosome, the presence of more than 60 closely spaced microsatellites on this chromosome will undoubtedly lead to the localization of additional disease genes. In order to consider cloned genes as potential candidates for disorders assigned to chromosome 4, it is important to collect and order all genes with respect to their chromosomal localization. Analysis of cytogenetically visible interstitial and terminal deletions should also be helpful in defining new disease gene loci and in mapping novel genes. These data represent the status quo of the integrated molecular map for chromosome 4.

References

  1. Am J Med Genet. 1992 Nov 15;44(5):696-8 - PubMed
  2. Nat Genet. 1994 Apr;6(4):391-3 - PubMed
  3. Nat Genet. 1993 Aug;4(4):381-6 - PubMed
  4. Hum Mol Genet. 1993 Oct;2(10):1673-8 - PubMed
  5. Am J Med Genet. 1982 Nov;13(3):341-3 - PubMed
  6. Clin Genet. 1990 Oct;38(4):314-7 - PubMed
  7. Genomics. 1991 Dec;11(4):1113-24 - PubMed
  8. J Med Genet. 1982 Apr;19(2):155-7 - PubMed
  9. J Med Genet. 1986 Oct;23(5):474-7 - PubMed
  10. Am J Hum Genet. 1974 Nov;26(6):715-22 - PubMed
  11. Nat Genet. 1994 Apr;6(4):384-90 - PubMed
  12. Am J Med Genet. 1983 Feb;14(2):391-3 - PubMed
  13. J Med Genet. 1989 Oct;26(10):652-4 - PubMed
  14. Hum Genet. 1977 Jun 10;37(1):87-91 - PubMed
  15. Cytogenet Cell Genet. 1994;65(4):238-42 - PubMed
  16. Lancet. 1989 Dec 16;2(8677):1449 - PubMed
  17. Hum Mol Genet. 1993 Oct;2(10):1535-40 - PubMed
  18. Am J Med Genet. 1988 Nov;31(3):533-48 - PubMed
  19. Genomics. 1993 Nov;18(2):230-5 - PubMed
  20. Clin Genet. 1992 Dec;42(6):281-7 - PubMed
  21. Am J Med Genet. 1989 Aug;33(4):553-4 - PubMed
  22. Cell. 1992 Feb 21;68(4):799-808 - PubMed
  23. Nat Genet. 1994 Mar;6(3):318-21 - PubMed
  24. Nature. 1985 Nov 7-13;318(6041):75-8 - PubMed
  25. Clin Genet. 1991 Jun;39(6):463-6 - PubMed
  26. J Med Genet. 1984 Jun;21(3):223-5 - PubMed
  27. Am J Med Genet. 1988 Nov;31(3):549-51 - PubMed
  28. Humangenetik. 1965;1(5):479-82 - PubMed
  29. J Med Genet. 1989 Dec;26(12):776-8 - PubMed
  30. J Med Genet. 1990 Jan;27(1):64-5 - PubMed
  31. Science. 1992 Oct 2;258(5079):67-86 - PubMed
  32. Genomics. 1992 Oct;14(2):209-19 - PubMed
  33. Cell. 1991 Feb 22;64(4):861-6 - PubMed
  34. Nat Genet. 1993 Jun;4(2):130-4 - PubMed
  35. Trends Neurosci. 1989 Oct;12(10):366-75 - PubMed
  36. Acta Ophthalmol (Copenh). 1964;42:97-107 - PubMed
  37. Neuron. 1992 Aug;9(2):349-56 - PubMed
  38. Clin Genet. 1985 Aug;28(2):166-72 - PubMed
  39. J Med Genet. 1988 Sep;25(9):628-30 - PubMed
  40. J Med Genet. 1970 Jun;7(2):164-70 - PubMed
  41. Nature. 1992 Oct 29;359(6398):794-801 - PubMed
  42. J Med Genet. 1992 Apr;29(4):259-61 - PubMed
  43. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8696-9 - PubMed
  44. Hum Mol Genet. 1993 Jul;2(7):901-7 - PubMed
  45. Am J Hum Genet. 1986 Sep;39(3):397-403 - PubMed
  46. Nat Genet. 1993 Dec;5(4):359-62 - PubMed
  47. Nature. 1991 Jul 4;352(6330):77-9 - PubMed
  48. Hum Genet. 1993 Jun;91(5):416-22 - PubMed
  49. Hum Mol Genet. 1993 Aug;2(8):1271-88 - PubMed
  50. Genomics. 1991 Nov;11(3):548-64 - PubMed
  51. Am J Med Genet. 1993 Jan 1;45(1):97-100 - PubMed
  52. Ann Genet. 1989;32(1):59-61 - PubMed
  53. J Med Genet. 1982 Dec;19(6):477 - PubMed
  54. J Pediatr Ophthalmol Strabismus. 1987 Jul-Aug;24(4):198-203 - PubMed
  55. Nat Genet. 1994 Mar;6(3):314-7 - PubMed
  56. Pediatrics. 1969 Oct;44(4):564-9 - PubMed
  57. Lancet. 1990 Sep 15;336(8716):651-3 - PubMed
  58. Nucleic Acids Res. 1991 Nov 25;19(22):6263-8 - PubMed
  59. Klin Padiatr. 1976 Nov;188(6):554-7 - PubMed
  60. J Med Genet. 1975 Jun;12(2):204-7 - PubMed
  61. Cell. 1991 Dec 20;67(6):1047-58 - PubMed
  62. Genomics. 1993 Jan;15(1):133-45 - PubMed
  63. Can J Ophthalmol. 1973 Jul;8(3):488-91 - PubMed
  64. Clin Genet. 1982 Feb;21(2):125-9 - PubMed
  65. Genomics. 1992 Nov;14(3):808-10 - PubMed
  66. J Med Genet. 1986 Aug;23(4):366-8 - PubMed
  67. J Med Genet. 1992 Jul;29(7):451-4 - PubMed
  68. Cell. 1993 Mar 26;72(6):971-83 - PubMed
  69. Nat Genet. 1992 May;1(2):104-8 - PubMed
  70. Nat Genet. 1992 Sep;2(1):26-30 - PubMed
  71. Clin Genet. 1981 Nov;20(5):323-7 - PubMed
  72. Genomics. 1991 Apr;9(4):570-5 - PubMed
  73. Am J Med Genet. 1989 Apr;32(4):520-3 - PubMed
  74. Am J Hum Genet. 1992 Sep;51(3):571-8 - PubMed
  75. Genomics. 1992 Jul;13(3):698-704 - PubMed
  76. Am J Med Genet. 1991 Jul 1;40(1):77-9 - PubMed
  77. Nat Genet. 1992 Nov;2(3):180-5 - PubMed
  78. Am J Med Genet. 1988 Nov;31(3):553-7 - PubMed
  79. Genomics. 1992 Oct;14(2):350-6 - PubMed
  80. Am J Med Genet. 1982 May;12(1):103-7 - PubMed
  81. Am J Med Genet. 1989 Jun;33(2):228-30 - PubMed
  82. Hum Genet. 1986 Jul;73(3):230-1 - PubMed
  83. Am J Hum Genet. 1991 Dec;49(6):1235-42 - PubMed
  84. Science. 1990 Oct 12;250(4978):245-50 - PubMed
  85. J Med Genet. 1978 Feb;15(1):30-4 - PubMed
  86. Clin Genet. 1984 Jun;25(6):500-21 - PubMed
  87. Nat Genet. 1993 Feb;3(2):103-12 - PubMed
  88. Genomics. 1992 Sep;14(1):131-6 - PubMed
  89. Hum Genet. 1993 Dec;92(6):629-30 - PubMed
  90. Am J Med Genet. 1985 Jun;21(2):337-45 - PubMed
  91. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8322-6 - PubMed
  92. Am J Med Genet. 1985 Jun;21(2):351-6 - PubMed
  93. Hum Genet. 1977 Nov 10;39(2):239-42 - PubMed
  94. Proc Natl Acad Sci U S A. 1989 Oct;86(20):7667-71 - PubMed
  95. J Med Genet. 1989 Oct;26(10):644-7 - PubMed
  96. Science. 1991 May 24;252(5009):1097-102 - PubMed
  97. EMBO J. 1989 Jun;8(6):1665-70 - PubMed
  98. J Med Genet. 1992 Jan;29(1):53-5 - PubMed
  99. Prenat Diagn. 1991 Feb;11(2):129-32 - PubMed
  100. Genomics. 1992 Aug;13(4):1311-3 - PubMed
  101. Clin Genet. 1980 Jun;17(6):375-84 - PubMed
  102. Science. 1986 Dec 5;234(4781):1243-7 - PubMed
  103. Nat Genet. 1993 Jun;4(2):181-6 - PubMed
  104. Genomics. 1993 Sep;17(3):599-603 - PubMed
  105. J Med Genet. 1973 Mar;10(1):83-5 - PubMed
  106. Science. 1993 Oct 1;262(5130):57-66 - PubMed
  107. Arch Ophthalmol. 1987 Mar;105(3):323 - PubMed
  108. FEBS Lett. 1989 Feb 27;244(2):361-4 - PubMed
  109. Clin Genet. 1986 May;29(5):439-44 - PubMed
  110. Genomics. 1993 Dec;18(3):467-72 - PubMed
  111. Genomics. 1992 Aug;13(4):1108-18 - PubMed
  112. Neuroscience. 1992 Dec;51(3):501-12 - PubMed
  113. Humangenetik. 1965;1(5):397-413 - PubMed
  114. Am J Hum Genet. 1977 Nov;29(6):641-2 - PubMed
  115. Am J Med Genet. 1992 Nov 1;44(4):449-54 - PubMed
  116. Nat Genet. 1992 Sep;2(1):46-9 - PubMed
  117. Hum Mutat. 1992;1(6):478-85 - PubMed
  118. Clin Genet. 1987 Apr;31(4):199-205 - PubMed
  119. Nat Genet. 1992 Aug;1(5):348-53 - PubMed
  120. Am J Hum Genet. 1992 Oct;51(4):755-62 - PubMed
  121. Trends Neurosci. 1990 Jul;13(7):281-5 - PubMed
  122. J Med Genet. 1992 Apr;29(4):256-8 - PubMed
  123. Nature. 1990 Aug 16;346(6285):648-51 - PubMed
  124. Genomics. 1992 Mar;12(3):492-6 - PubMed
  125. Nature. 1989 Apr 13;338(6216):582-5 - PubMed
  126. Hum Genet. 1991 Mar;86(5):481-3 - PubMed
  127. Clin Genet. 1982 Dec;22(6):348-55 - PubMed
  128. Prenat Diagn. 1985 May-Jun;5(3):209-14 - PubMed
  129. Br J Ophthalmol. 1979 Jan;63(1):40-4 - PubMed
  130. Cytogenet Cell Genet. 1994;65(3):206-18 - PubMed
  131. Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7474-6 - PubMed
  132. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9695-9 - PubMed
  133. Cell. 1993 Jul 16;74(1):127-34 - PubMed
  134. Cell. 1993 Sep 24;74(6):955-6 - PubMed
  135. J Pediatr. 1977 Feb;90(2):250-2 - PubMed
  136. Hum Genet. 1978 Oct 19;44(1):105-8 - PubMed
  137. Somat Cell Mol Genet. 1991 Jul;17(4):421-5 - PubMed
  138. J Med Genet. 1992 Jun;29(6):400-6 - PubMed
  139. Hum Genet. 1990 Apr;84(5):473-6 - PubMed
  140. Nature. 1988 Sep 1;335(6185):76-9 - PubMed
  141. Hum Mol Genet. 1993 Dec;2(12):2063-7 - PubMed
  142. Nat Genet. 1993 Jul;4(3):221-6 - PubMed
  143. J Med Genet. 1970 Jun;7(2):171-6 - PubMed
  144. Hum Mol Genet. 1993 Oct;2(10):1571-5 - PubMed
  145. Nature. 1987 Jul 16-22;328(6127):221-7 - PubMed
  146. J Med Genet. 1976 Dec;13(6):522-5 - PubMed

MeSH terms

Publication Types