Display options
Share it on

Hum Genet. 1994 May;93(5):611-2. doi: 10.1007/BF00202837.

A transcribed polymorphism and sub-localisation of MDM2.

Human genetics

J Heighway, E L Mitchell, D Jones, G R White, M F Santibáñez Koref

Affiliations

  1. CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie CRC Research Centre, Manchester, UK.

PMID: 8168847 DOI: 10.1007/BF00202837

Abstract

An NlaIV polymorphism in the 5' untranslated region of the MDM2 gene is described. MDM2 was sublocalised by fluorescence in situ hybridisation with a yeast artificial chromosome probe to 12q14.3-12q15. We demonstrate the use of the polymorphism to assess allelic imbalance in breast tumours.

References

  1. Nature. 1992 Jul 2;358(6381):80-3 - PubMed
  2. Science. 1990 Jan 5;247(4938):64-9 - PubMed
  3. Lancet. 1992 Aug 1;340(8814):259-63 - PubMed
  4. Nucleic Acids Res. 1990 Apr 25;18(8):1951-6 - PubMed
  5. Genomics. 1991 Dec;11(4):1079-87 - PubMed
  6. Science. 1991 Jul 5;253(5015):49-53 - PubMed
  7. Mol Cell Biol. 1993 Jan;13(1):301-6 - PubMed
  8. Lancet. 1991 Dec 14;338(8781):1490-1 - PubMed
  9. Br J Haematol. 1993 Sep;85(1):179-81 - PubMed
  10. Genes Chromosomes Cancer. 1990 Nov;2(4):278-89 - PubMed
  11. Cancer Res. 1993 Jun 15;53(12 ):2736-9 - PubMed
  12. J Med Genet. 1992 Apr;29(4):249-50 - PubMed

Substances

MeSH terms

Publication Types