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Williamson KA, Van Heyningen V. Towards an understanding of Wilms' tumour. Int J Exp Pathol. 1994;75(3):147-55
Williamson, K. A., & Van Heyningen, V. (1994). Towards an understanding of Wilms' tumour. International journal of experimental pathology, 75(3), 147-55.
Williamson, K A, and Van Heyningen, V. "Towards an understanding of Wilms' tumour." International journal of experimental pathology vol. 75,3 (1994): 147-55.
Williamson KA, Van Heyningen V. Towards an understanding of Wilms' tumour. Int J Exp Pathol. 1994 Jun;75(3):147-55. PMID: 8086311; PMCID: PMC2001799.
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Wiley Free PMC Article

Int J Exp Pathol. 1994 Jun;75(3):147-55.

Towards an understanding of Wilms' tumour.

International journal of experimental pathology

K A Williamson, V Van Heyningen

Affiliations

  1. MRC Human Genetics Unit, Western General Hospital, Edinburgh, Scotland.

PMID: 8086311 PMCID: PMC2001799
Free PMC Article

Abstract

Many areas of research are contributing to our understanding of WT and the role of WT1 in development of the renal and genitourinary systems. Characterization of putative target genes and the control of their expression continues. The importance of isoform ratios and imprinting effects are also under active investigation, often using animal models. The accumulating mutation data, together with evolutionary studies, illuminate WT1 structure-function relationships, highlighting the regions critical in normal development and tumorigenesis. And last, but by no means least, the hunt for the WT2 and WT3 genes continues.

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