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Birnbacher R, Balzar E, Aufricht C, et al. Tubulointerstitial nephritis and uveitis: an immunological disorder?. Pediatr Nephrol. 1995;9(2):193-5doi: 10.1007/BF00860744.
Birnbacher, R., Balzar, E., Aufricht, C., Schmaldienst, S., Woloszczuk, W., & Förster, E. (1995). Tubulointerstitial nephritis and uveitis: an immunological disorder?. Pediatric nephrology (Berlin, Germany), 9(2), 193-5. https://doi.org/10.1007/BF00860744
Birnbacher, R, et al. "Tubulointerstitial nephritis and uveitis: an immunological disorder?." Pediatric nephrology (Berlin, Germany) vol. 9,2 (1995): 193-5. doi: https://doi.org/10.1007/BF00860744
Birnbacher R, Balzar E, Aufricht C, Schmaldienst S, Woloszczuk W, Förster E. Tubulointerstitial nephritis and uveitis: an immunological disorder?. Pediatr Nephrol. 1995 Apr;9(2):193-5. doi: 10.1007/BF00860744. PMID: 7794717.
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Pediatr Nephrol. 1995 Apr;9(2):193-5. doi: 10.1007/BF00860744.

Tubulointerstitial nephritis and uveitis: an immunological disorder?.

Pediatric nephrology (Berlin, Germany)

R Birnbacher, E Balzar, C Aufricht, S Schmaldienst, W Woloszczuk, E Förster

Affiliations

  1. Department of Paediatrics, University of Vienna, Austria.

PMID: 7794717 DOI: 10.1007/BF00860744

Abstract

A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined as the clinical symptoms improved. This may be interpreted as an indication of their significance as markers in the pathogenesis of this syndrome or as part of a microbial-triggered immune response.

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