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Beck C, Schmidt CL. 10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière. Arch Otorhinolaryngol. 1978;221(2):149-52doi: 10.1007/BF00455886.
Beck, C., & Schmidt, C. L. (1978). 10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière. Archives of oto-rhino-laryngology, 221(2), 149-52. https://doi.org/10.1007/BF00455886
Beck, C, and Schmidt, C L. "10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière." Archives of oto-rhino-laryngology vol. 221,2 (1978): 149-52. doi: https://doi.org/10.1007/BF00455886
Beck C, Schmidt CL. 10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière. Arch Otorhinolaryngol. 1978 Sep 28;221(2):149-52. doi: 10.1007/BF00455886. PMID: 751619.
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Arch Otorhinolaryngol. 1978 Sep 28;221(2):149-52. doi: 10.1007/BF00455886.

10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière.

Archives of oto-rhino-laryngology

C Beck, C L Schmidt

PMID: 751619 DOI: 10.1007/BF00455886

Abstract

During the last 10 years a total of 83 patients with severe cases of unilateral Morbus Menière were treated in our clinic. The proposed therapy was to administer streptomycin (gentamycinsulfate) intratympanically by applying two different ways of procedure. In the first group of 40 patients we attempted to destroy the vestibular organ without harming the cochlea whereby we avoided surgical intervention. In the second group of 43 patients we integrated more recent findings in the pathophysiological mechanism underlying the pathogenesis of Morbus Menière into our therapeutic considerations and attempted to exclusively destroy the secretorial epithelium with minimal dosages of aminoclycoside antibiotics. The results after treatment were clearly better for the second group of patients.

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