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Herlitz J, Hartford M, Dellborg M, et al. Optimal treatment after acute myocardial infarction in the elderly. Drugs Aging. 1995;6(3):181-91doi: 10.2165/00002512-199506030-00002.
Herlitz, J., Hartford, M., Dellborg, M., & Karlson, B. W. (1995). Optimal treatment after acute myocardial infarction in the elderly. Drugs & aging, 6(3), 181-91. https://doi.org/10.2165/00002512-199506030-00002
Herlitz, J, et al. "Optimal treatment after acute myocardial infarction in the elderly." Drugs & aging vol. 6,3 (1995): 181-91. doi: https://doi.org/10.2165/00002512-199506030-00002
Herlitz J, Hartford M, Dellborg M, Karlson BW. Optimal treatment after acute myocardial infarction in the elderly. Drugs Aging. 1995 Mar;6(3):181-91. doi: 10.2165/00002512-199506030-00002. PMID: 7620232.
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Drugs Aging. 1995 Mar;6(3):181-91. doi: 10.2165/00002512-199506030-00002.

Optimal treatment after acute myocardial infarction in the elderly.

Drugs & aging

J Herlitz, M Hartford, M Dellborg, B W Karlson

Affiliations

  1. Division of Cardiology, Sahlgrenska Hospital, Göteborg, Sweden.

PMID: 7620232 DOI: 10.2165/00002512-199506030-00002

Abstract

Elderly patients with acute myocardial infarction (AMI) more often have a previous history of cardiovascular disease than do younger patients. Furthermore, they less frequently present with typical symptoms and a typical electrocardiogram pattern. Whereas age is the most important predictor for mortality after AMI, the relationship between age and morbidity is more complex. Treatment of elderly patients with AMI is very similar to treatment of younger patients. However, the risk of intolerability to various drugs increases with age, and in many instances doses have to be adjusted. In many trials, the number of lives saved with various interventions seem, if anything, to be more numerous among the elderly. However, it should be remembered that experience with various treatments in the elderly (patients aged > 80 years) is limited. Whether experiences with people aged up to 80 years can be extrapolated to higher age groups is debatable. With increasing age, there is an increased frequency of other disabling diseases, as well as generalised atherosclerosis. It might very well be that even in the elderly it is possible to relieve symptoms and improve morbidity, even though the effects on the prognosis are likely to be less marked.

References

  1. Am J Cardiol. 1991 May 15;67(13):1051-5 - PubMed
  2. Age Ageing. 1987 Mar;16(2):125-7 - PubMed
  3. J Am Coll Cardiol. 1991 Mar 1;17(3):599-603 - PubMed
  4. Am J Cardiol. 1989 Jun 15;63(20):1526-8 - PubMed
  5. J Thorac Cardiovasc Surg. 1991 Oct;102(4):532-8 - PubMed
  6. Age Ageing. 1987 Jul;16(4):239-43 - PubMed
  7. Circulation. 1982 Dec;66(6):1179-84 - PubMed
  8. N Engl J Med. 1993 Mar 11;328(10 ):685-91 - PubMed
  9. Curr Probl Cardiol. 1992 Oct;17(10):609-90 - PubMed
  10. Lancet. 1986 Jul 12;2(8498):57-66 - PubMed
  11. Am J Cardiol. 1985 Nov 22;56(14):47G-54G - PubMed
  12. Can J Cardiol. 1990 Jul-Aug;6(6):241-6 - PubMed
  13. Clin Cardiol. 1988 Aug;11(8):519-23 - PubMed
  14. J Am Coll Cardiol. 1991 May;17(6):1245-50 - PubMed
  15. Circulation. 1978 Oct;58(4):689-99 - PubMed
  16. N Engl J Med. 1989 Aug 10;321(6):406-12 - PubMed
  17. Lancet. 1994 May 7;343(8906):1115-22 - PubMed
  18. Eur Heart J. 1985 Mar;6(3):199-226 - PubMed
  19. Mod Concepts Cardiovasc Dis. 1976 Oct;45(10):129-33 - PubMed
  20. Acta Cardiol. 1987;42(1):59-68 - PubMed
  21. Cardiology. 1992;80(3-4):215-25 - PubMed
  22. N Engl J Med. 1993 Mar 11;328(10 ):673-9 - PubMed
  23. Lancet. 1982 May 22;1(8282):1142-7 - PubMed
  24. Am J Cardiol. 1991 Nov 15;68(13):1316-20 - PubMed
  25. Lancet. 1992 Jun 27;339(8809):1553-8 - PubMed
  26. N Engl J Med. 1973 Feb 8;288(6):281-4 - PubMed
  27. Eur Heart J. 1987 May;8(5):503-9 - PubMed
  28. J Am Coll Cardiol. 1985 Jun;5(6):1428-37 - PubMed
  29. Lancet. 1984 Oct 20;2(8408):883-6 - PubMed
  30. Circulation. 1988 Oct;78(4):906-19 - PubMed
  31. J Am Coll Cardiol. 1992 Mar 1;19(3):639-46 - PubMed
  32. Acta Med Scand Suppl. 1975;586:1-64, 1-35 - PubMed
  33. J Am Coll Cardiol. 1987 Aug;10(2 Suppl A):73A-76A - PubMed
  34. J Am Geriatr Soc. 1987 Oct;35(10):915-9 - PubMed
  35. J Am Geriatr Soc. 1979 Apr;27(4):145-51 - PubMed
  36. Am J Cardiol. 1986 Aug 1;58(3):203-9 - PubMed
  37. Practitioner. 1984 Sep;228(1395):841-3 - PubMed
  38. Lancet. 1986 Feb 22;1(8478):397-402 - PubMed
  39. Circulation. 1992 Sep;86(3):774-9 - PubMed
  40. Am J Med. 1993 Mar;94(3):265-73 - PubMed
  41. Arch Intern Med. 1989 Dec;149(12):2694-8 - PubMed
  42. Prog Cardiovasc Dis. 1980 Nov-Dec;23(3):187-224 - PubMed
  43. Am J Cardiol. 1988 Mar 25;61(9):2E-3E - PubMed
  44. J Am Geriatr Soc. 1992 Jan;40(1):19-22 - PubMed
  45. Br Heart J. 1984 Apr;51(4):438-44 - PubMed
  46. South Med J. 1984 Sep;77(9):1127-9 - PubMed
  47. Acta Med Scand Suppl. 1976;587:201-8 - PubMed
  48. N Engl J Med. 1992 Sep 3;327(10):669-77 - PubMed
  49. Am J Emerg Med. 1992 Sep;10(5):406-12 - PubMed
  50. J Cardiovasc Pharmacol. 1990 Jun;15(6):998-1009 - PubMed
  51. Eur Heart J. 1988 Mar;9(3):284-90 - PubMed
  52. Lancet. 1993 Oct 2;342(8875):821-8 - PubMed
  53. J Am Coll Cardiol. 1990 Oct;16(4):770-8 - PubMed
  54. J Am Coll Cardiol. 1992 Dec;20(7):1482-9 - PubMed
  55. N Engl J Med. 1992 Sep 3;327(10):678-84 - PubMed
  56. Am J Cardiol. 1990 Feb 15;65(7):519-21 - PubMed
  57. J Am Coll Cardiol. 1990 Oct;16(4):784-92 - PubMed
  58. Acta Med Scand. 1979;206(3):189-92 - PubMed
  59. Chest. 1989 Feb;95(2 Suppl):52S-72S - PubMed
  60. Br Med J. 1978 Feb 4;1(6108):279-80 - PubMed
  61. Eur Heart J. 1994 Jan;15(1):5-9 - PubMed
  62. Chest. 1987 Sep;92(3):481-5 - PubMed
  63. Am J Cardiol. 1992 Apr 1;69(9):968-9 - PubMed
  64. N Engl J Med. 1983 Mar 17;308(11):614-8 - PubMed
  65. J Am Coll Cardiol. 1992 Mar 1;19(3):647-53 - PubMed
  66. Cardiovasc Clin. 1977;8(3):65-77 - PubMed
  67. Lancet. 1994 Feb 5;343(8893):311-22 - PubMed
  68. N Engl J Med. 1981 Apr 2;304(14 ):801-7 - PubMed
  69. Lancet. 1992 Mar 28;339(8796):753-70 - PubMed
  70. JAMA. 1982 Mar 26;247(12):1707-14 - PubMed
  71. Br J Hosp Med. 1988 Oct;40(4):300-1, 304-6 - PubMed
  72. JAMA. 1988 Oct 7;260(13):1910-6 - PubMed
  73. Lancet. 1988 Aug 13;2(8607):349-60 - PubMed
  74. Am J Cardiol. 1969 Nov;24(5):659-65 - PubMed
  75. N Engl J Med. 1991 Dec 26;325(26):1825-30 - PubMed
  76. Eur Heart J. 1991 Oct;12(10):1112-31 - PubMed
  77. Acta Med Scand. 1985;217(3):293-8 - PubMed
  78. Am J Cardiol. 1988 Nov 1;62(13):860-7 - PubMed
  79. Int J Cardiol. 1988 Aug;20(2):221-30 - PubMed
  80. Am J Cardiol. 1983 May 1;51(8):1282-8 - PubMed
  81. Circulation. 1992 Sep;86(3):764-73 - PubMed
  82. Lancet. 1981 Oct 17;2(8251):823-7 - PubMed
  83. N Engl J Med. 1991 Oct 17;325(16):1117-22 - PubMed
  84. N Engl J Med. 1993 Sep 2;329(10 ):673-82 - PubMed
  85. Ann Intern Med. 1993 Jan 15;118(2):99-105 - PubMed
  86. N Engl J Med. 1985 Oct 24;313(17):1055-8 - PubMed
  87. Am J Cardiol. 1985 Jun 1;55(13 Pt 1):1609-13 - PubMed
  88. N Engl J Med. 1993 Mar 11;328(10):680-4 - PubMed
  89. Eur Heart J. 1991 Oct;12(10):1081-3 - PubMed
  90. Circulation. 1993 Dec;88(6):2575-81 - PubMed

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