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Nature Publishing Group

Heredity (Edinb). 1975 Aug;35(1):121-6. doi: 10.1038/hdy.1975.73.

Genetical variation for enzyme activity in a population of Drosophila melanogaster. III. Dominance relationships for alcohol dehydrogenase activity.

Heredity

A J Birley, B W Barnes

PMID: 810464 DOI: 10.1038/hdy.1975.73

Abstract

Four inbred lines, two homozygous AdhS/S and two homozygous AdhF/F, were extracted from a laboratory cage population of Drosophila melanogaster and crossed in all combinations. Directional dominance for low ADH activity was present and confined to AdhF/S heterozygotes. The remaining genetical differences between the four lines for ADH activity were due to additive genetical variation. The frequency of the AdhS allele in the population was 0-89. The observed directional dominance for low ADH activity in AdhF/S heterozygotes corresponded to the general direction of selection for ADH activity within the population.

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