Display options
Share it on

Arch Dis Child. 1981 Jun;56(6):464-7. doi: 10.1136/adc.56.6.464.

Amyloidosis in children with familial Mediterranean fever.

Archives of disease in childhood

A Ludomirsky, J Passwell, H Boichis

PMID: 7259278 PMCID: PMC1627456 DOI: 10.1136/adc.56.6.464

Abstract

The clinical and laboratory findings of 35 children with familial Mediterranean fever who developed amyloidosis are described. The types, frequency, and severity of attacks of familial Mediterranean fever in these children were no different from patients with this disease without amyloidosis. Although amyloid was widely deposited in all tissues, the major clinical manifestations of the amyloidosis were proteinuria, the nephrotic syndrome, and progressive renal failure. Only 20% of the patients were alive 5 years after the first appearance of proteinuria.

References

  1. Ann Rheum Dis. 1962 Sep;21:298-9 - PubMed
  2. Ann Intern Med. 1977 Nov;87(5):579-80 - PubMed
  3. N Engl J Med. 1976 Jan 15;294(3):170-1 - PubMed
  4. Ann Rheum Dis. 1971 May;30(3):331 - PubMed
  5. Am J Med. 1967 Aug;43(2):227-53 - PubMed
  6. Ann Rheum Dis. 1968 Mar;27(2):137-45 - PubMed
  7. J Clin Invest. 1972 Oct;51(10):2773-6 - PubMed
  8. J Pathol Bacteriol. 1964 Jul;88:15-34 - PubMed
  9. Lancet. 1972 Sep 23;2(7778):616-9 - PubMed
  10. Arthritis Rheum. 1978 Jan-Feb;21(1):153-60 - PubMed
  11. Ann Intern Med. 1977 Nov;87(5):568-70 - PubMed
  12. J Exp Med. 1974 Oct 1;140(4):1102-7 - PubMed
  13. Isr J Med Sci. 1974 Jul;10(7):787-9 - PubMed
  14. Pathol Microbiol (Basel). 1968;31(2):85-92 - PubMed
  15. N Engl J Med. 1974 Oct 31;291(18):934-7 - PubMed
  16. J Pediatr. 1969 Feb;74(2):272-82 - PubMed
  17. N Engl J Med. 1974 Oct 31;291(18):932-4 - PubMed
  18. Semin Hematol. 1973 Jan;10(1):65-86 - PubMed
  19. Arthritis Rheum. 1970 Nov-Dec;13(6):902-15 - PubMed
  20. Arch Intern Med. 1979 Oct;139(10):1135-8 - PubMed
  21. Arch Intern Med. 1962 Aug;110:150-4 - PubMed
  22. N Engl J Med. 1977 Oct 13;297(15):821-3 - PubMed
  23. N Engl J Med. 1975 Nov 27;293(22):1131-3 - PubMed

MeSH terms

Publication Types