Arch Int Pharmacodyn Ther. 1981;253(2):180-91.
Archives internationales de pharmacodynamie et de therapie
R Phillips, G L Plaa
PMID: 7325758
The biliary excretion of diazepam metabolites was found in rats. Equivalent dosages of diazepam were administered orally and intraperitoneally. The biliary excretion was dose-dependent and was greater following intraperitoneal administration. After intravenous administration, a greater percentage of the diazepam dosage administered was excreted into the bile. Repetitive intravenous administrations yielded results which approached those observed after intraperitoneally administered dosages given as a bolus.
