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Atypon Free PMC Article

Proc Natl Acad Sci U S A. 1981 May;78(5):3147-50. doi: 10.1073/pnas.78.5.3147.

Genes in mice that affect susceptibility to cortisone-induced cleft palate are closely linked to Ir genes on chromosomes 2 and 17.

Proceedings of the National Academy of Sciences of the United States of America

D L Gasser, L Mele, D D Lees, A S Goldman

PMID: 6942422 PMCID: PMC319517 DOI: 10.1073/pnas.78.5.3147
Free PMC Article

Abstract

Inbred and congeneic strains of mice have been examined for susceptibility to cortisone-induced cleft palate, and the role of genes linked to H-2 on chromosome 17 has been confirmed. Increasing degrees of susceptibility were associated with the H-2d, H-2b, H-2k, and H-2a haplotypes, respectively, with H-2q and H-2s also being associated with fairly high levels of susceptibility. Evidence was obtained that suggests that one gene maps within the B region of H-2, and that a second H-2 linked gene which acts by complementation maps to the right of E. Another gene affecting this trait is closely linked to the H-3 and Ir-2 loci on the second chromosome.

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References

  1. Biochemistry. 1980 Sep 30;19(20):4556-64 - PubMed
  2. Genetics. 1977 Feb;85(2):289-302 - PubMed
  3. Eur J Immunol. 1973 Dec;3(12):754-61 - PubMed
  4. Nature. 1977 Feb 17;265(5595):643-5 - PubMed
  5. Science. 1974 Feb 22;183(4126):757-9 - PubMed
  6. McGill Med J. 1950 Dec;19(4):245-9 - PubMed
  7. Teratology. 1977 Jun;15(3):249-51 - PubMed
  8. Contemp Top Immunobiol. 1980;9:231-53 - PubMed
  9. Am J Med. 1972 Jan;52(1):1-8 - PubMed
  10. Transplantation. 1973 Jan;15(1):137-53 - PubMed
  11. Nature. 1978 Sep 14;275(5676):136-8 - PubMed
  12. J Exp Med. 1972 Nov 1;136(5):1231-40 - PubMed
  13. Proc Soc Exp Biol Med. 1978 Sep;158(4):618-21 - PubMed
  14. Biochemistry. 1980 Jan 8;19(1):49-54 - PubMed
  15. Teratology. 1975 Oct;12(2):165-71 - PubMed
  16. Proc R Soc Lond B Biol Sci. 1978 Jun 5;202(1146):117-58 - PubMed
  17. Proc Natl Acad Sci U S A. 1975 Jul;72(7):2644-8 - PubMed
  18. Genetics. 1954 Mar;39(2):185-96 - PubMed
  19. Lancet. 1974 Jun 22;1(7869):1269-75 - PubMed
  20. Experientia. 1979 Aug 15;35(8):1103-4 - PubMed
  21. Pediatrics. 1957 Apr;19(4 Part 2):782-7 - PubMed
  22. Adv Immunol. 1974;18:1-66 - PubMed
  23. J Immunol. 1969 Jul;103(1):66-70 - PubMed
  24. Pediatrics. 1951 Oct;8(4):527-33 - PubMed
  25. Science. 1972 Jan 21;175(4019):273-9 - PubMed
  26. Differentiation. 1979;13(3):141-54 - PubMed

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