J Clin Gastroenterol. 1980 Sep;2(3):229-31. doi: 10.1097/00004836-198009000-00004.

Cromolyn sodium in the treatment of ulcerative colitis.

Journal of clinical gastroenterology

R R Babb

PMID: 6778911 DOI: 10.1097/00004836-198009000-00004

Abstract

An immediate hypersensitivity reaction with mast cell degranulation may be of importance in the pathogenesis of ulcerative colitis. Cromolyn sodium stabilizes the mast cell membrane, and thus could have potential benefit in the treatment of this disease. The few clinical studies published to date are difficult to interpret, and have not established the therapeutic benefit of cromolyn sodium in ulcerative colitis.

Substances

• Cromolyn Sodium

MeSH terms

• Cell Membrane / drug effects
• Cell Membrane / immunology
• Colitis, Ulcerative / drug therapy
• Colitis, Ulcerative / etiology
• Colitis, Ulcerative / immunology
• Cromolyn Sodium / therapeutic use
• Humans
• Hypersensitivity, Immediate / drug therapy
• Mast Cells / pathology

Publication Types

• Journal Article