Display options
Share it on

Br J Exp Pathol. 1978 Apr;59(2):190-5.

Association of foetal wastage with influenza infection during ferret pregnancy.

British journal of experimental pathology

M H Collie, C Sweet, D Cavanagh, H Smith

PMID: 656319 PMCID: PMC2041328
Free PMC Article

Abstract

Inoculation of influenza virus into pregnant ferrets during the late gestational period was investigated. Foetal resorption followed intracardial inoculation of a large dose of influenza virus (10(9.4) EBID50) and a 100-fold lower dose caused lower litter sizes at birth. The possible role of fever in foetal resorptions was largely discounted by 2 observations: a non-pyrexic dose inoculated intracardially into the pregnant ferret still had detrimental effects on foetal viability; influenza virus inoculated intranasally caused a pyrexia but did not affect the progeny. The potential of the ferret as a model for studying the possible adverse effects of influenza during pregnancy is discussed.

Similar articles

References

  1. Acta Virol. 1975 May;19(3):259 - PubMed
  2. Przegl Lek. 1976;33(9):787-92 - PubMed
  3. Br J Exp Pathol. 1977 Apr;58(2):133-9 - PubMed
  4. Br J Exp Pathol. 1977 Apr;58(2):113-23 - PubMed
  5. Teratology. 1976 Dec;14(3):323-6 - PubMed
  6. Acta Odontol Scand. 1975;33(5):259-67 - PubMed
  7. Proc Soc Exp Biol Med. 1975 Sep;149(4):881-3 - PubMed
  8. Br J Exp Pathol. 1976 Feb;57(1):37-48 - PubMed
  9. Lancet. 1972 Feb 5;1(7745):320-1 - PubMed
  10. Immunochemistry. 1974 Dec;11(12):823-6 - PubMed
  11. Bacteriol Rev. 1974 Dec;38(4):356-70 - PubMed
  12. Br J Exp Pathol. 1972 Feb;53(1):31-6 - PubMed
  13. Tohoku J Exp Med. 1966 Aug 25;89(4):321-40 - PubMed
  14. Br J Exp Pathol. 1970 Feb;51(1):1-6 - PubMed
  15. J Hyg (Lond). 1958 Mar;56(1):151-62 - PubMed
  16. Am J Obstet Gynecol. 1958 Oct;76(4):897-902 - PubMed
  17. Acta Pathol Microbiol Scand. 1960;49:114-26 - PubMed
  18. J Hyg (Lond). 1977 Oct;79(2):249-57 - PubMed

Substances

MeSH terms

Publication Types

LinkOut - more resources