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Taylor CF, Britton P, van Heyningen S. Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions. Biochem J. 1983;209(3):897-9doi: 10.1042/bj2090897.
Taylor, C. F., Britton, P., & van Heyningen, S. (1983). Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions. The Biochemical journal, 209(3), 897-9. https://doi.org/10.1042/bj2090897
Taylor, C F, et al. "Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions." The Biochemical journal vol. 209,3 (1983): 897-9. doi: https://doi.org/10.1042/bj2090897
Taylor CF, Britton P, van Heyningen S. Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions. Biochem J. 1983 Mar 01;209(3):897-9. doi: 10.1042/bj2090897. PMID: 6870797; PMCID: PMC1154173.
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Biochem J. 1983 Mar 01;209(3):897-9. doi: 10.1042/bj2090897.

Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions.

The Biochemical journal

C F Taylor, P Britton, S van Heyningen

PMID: 6870797 PMCID: PMC1154173 DOI: 10.1042/bj2090897
Free PMC Article

Abstract

Quantitative comparison of the amino acid compositions of the heavy and light chains of tetanus toxin by the method of Cornish-Bowden [(1983) Methods Enzymol. 91, 60-75)] suggests strongly that there is sequence homology between the two chains and that the heavy chain has two similar halves. Examination (by electrophoresis in polyacrylamide gels in the presence of sodium dodecyl sulphate) of peptides produced from the chains by proteolytic cleavage supports this idea.

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