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Gisselbrecht C, Belpomme D, Mignot L, et al. Chemotherapy of carcinomas of the digestive tract. Recent Results Cancer Res. 1982;80:296-302doi: 10.1007/978-3-642-81685-7_47.
Gisselbrecht, C., Belpomme, D., Mignot, L., Marty, M., Mathé, G., & Boiron, M. (1982). Chemotherapy of carcinomas of the digestive tract. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 80296-302. https://doi.org/10.1007/978-3-642-81685-7_47
Gisselbrecht, C, et al. "Chemotherapy of carcinomas of the digestive tract." Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer vol. 80 (1982): 296-302. doi: https://doi.org/10.1007/978-3-642-81685-7_47
Gisselbrecht C, Belpomme D, Mignot L, Marty M, Mathé G, Boiron M. Chemotherapy of carcinomas of the digestive tract. Recent Results Cancer Res. 1982;80:296-302. doi: 10.1007/978-3-642-81685-7_47. PMID: 6799999.
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Recent Results Cancer Res. 1982;80:296-302. doi: 10.1007/978-3-642-81685-7_47.

Chemotherapy of carcinomas of the digestive tract.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

C Gisselbrecht, D Belpomme, L Mignot, M Marty, G Mathé, M Boiron

PMID: 6799999 DOI: 10.1007/978-3-642-81685-7_47

Abstract

Adjuvant chemotherapy trials in gastric and colorectal carcinomas are reviewed and no clear benefit from such treatment could be observed. To improve existing chemotherapy regimens, several pilot studies were performed in 95 gastric cancer and 85 colorectal carcinomas patients. Response rate for gastric carcinomas using the mitomycin C plus adriamycin plus 5-fluorouracil (5-FU) (FAM) regimen was 40% and was not improved by the addition of nitrosoureas. In colorectal carcinomas none of the combinations used gave better results than 5-FU alone. Fourteen patients with esophageal carcinoma were treated with combination CDDP and the response rate was as high as 50%.

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