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Stella L, Crescenti A, Torri G. Effect of naloxone on the loss of consciousness induced by i.v. anaesthetic agents in man. Br J Anaesth. 1984;56(4):369-73doi: 10.1093/bja/56.4.369.
Stella, L., Crescenti, A., & Torri, G. (1984). Effect of naloxone on the loss of consciousness induced by i.v. anaesthetic agents in man. British journal of anaesthesia, 56(4), 369-73. https://doi.org/10.1093/bja/56.4.369
Stella, L, et al. "Effect of naloxone on the loss of consciousness induced by i.v. anaesthetic agents in man." British journal of anaesthesia vol. 56,4 (1984): 369-73. doi: https://doi.org/10.1093/bja/56.4.369
Stella L, Crescenti A, Torri G. Effect of naloxone on the loss of consciousness induced by i.v. anaesthetic agents in man. Br J Anaesth. 1984 Apr;56(4):369-73. doi: 10.1093/bja/56.4.369. PMID: 6712851.
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Elsevier Science

Br J Anaesth. 1984 Apr;56(4):369-73. doi: 10.1093/bja/56.4.369.

Effect of naloxone on the loss of consciousness induced by i.v. anaesthetic agents in man.

British journal of anaesthesia

L Stella, A Crescenti, G Torri

PMID: 6712851 DOI: 10.1093/bja/56.4.369
Free Article

Abstract

The effect of a specific opioid antagonist, naloxone, was studied in two comparable groups of patients who received i.v. the dose of an anaesthetic agent required to produce loss of consciousness in 50% of subjects. The first group received naloxone 0.006 mg kg-1 5 min before induction of anaesthesia; the second group received a similar volume of saline solution. Thiopentone, Althesin, diazepam, ketamine and propanidid were studied. The differences in percentage of unconscious patients between the naloxone-treated group and the control group were statistically significant for diazepam, ketamine and propanidid. Naloxone did not modify the induction of anaesthesia with thiopentone or Althesin.

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