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Kauppinen K, Stubb S. Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period. Acta Derm Venereol. 1984;64(4):320-4
Kauppinen, K., & Stubb, S. (1984). Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period. Acta dermato-venereologica, 64(4), 320-4.
Kauppinen, K, and Stubb, S. "Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period." Acta dermato-venereologica vol. 64,4 (1984): 320-4.
Kauppinen K, Stubb S. Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period. Acta Derm Venereol. 1984;64(4):320-4. PMID: 6209890.
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Acta Derm Venereol. 1984;64(4):320-4.

Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period.

Acta dermato-venereologica

K Kauppinen, S Stubb

PMID: 6209890

Abstract

A series of 446 inpatients with drug eruption was studied to determine the causative agent and the clinical type. In over a half of the cases a provocation test confirmed the drug responsible for the reaction. Sulphonamides/trimethoprim and ampicillin/penicillin followed by phenazones were the most frequent agents causing eruptions. Sulphonamides were also the most common drugs inducing Lyell's and Stevens-Johnson syndromes. Phenazones and barbiturates were the main causes of fixed eruptions. The frequency of inpatients having drug eruption was decreased in the 1971-80 series compared with the earlier one from 1961-70. Also the frequency of Lyell's and Stevens-Johnson syndromes was lower in the latter decade than in the earlier one.

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