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Itoh S, Matsuo S, Ichinoe A, et al. Nonalcoholic steatohepatitis and cirrhosis with Mallory's hyalin with ultrastructural study of one case. Dig Dis Sci. 1982;27(4):341-6doi: 10.1007/BF01296754.
Itoh, S., Matsuo, S., Ichinoe, A., Yamaba, Y., & Miyazawa, M. (1982). Nonalcoholic steatohepatitis and cirrhosis with Mallory's hyalin with ultrastructural study of one case. Digestive diseases and sciences, 27(4), 341-6. https://doi.org/10.1007/BF01296754
Itoh, S, et al. "Nonalcoholic steatohepatitis and cirrhosis with Mallory's hyalin with ultrastructural study of one case." Digestive diseases and sciences vol. 27,4 (1982): 341-6. doi: https://doi.org/10.1007/BF01296754
Itoh S, Matsuo S, Ichinoe A, Yamaba Y, Miyazawa M. Nonalcoholic steatohepatitis and cirrhosis with Mallory's hyalin with ultrastructural study of one case. Dig Dis Sci. 1982 Apr;27(4):341-6. doi: 10.1007/BF01296754. PMID: 6175490.
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Dig Dis Sci. 1982 Apr;27(4):341-6. doi: 10.1007/BF01296754.

Nonalcoholic steatohepatitis and cirrhosis with Mallory's hyalin with ultrastructural study of one case.

Digestive diseases and sciences

S Itoh, S Matsuo, A Ichinoe, Y Yamaba, M Miyazawa

PMID: 6175490 DOI: 10.1007/BF01296754

Abstract

Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 years old, comprised two females and one male with steatohepatitis and three females with micronodular cirrhosis. They showed obesity, hepatomegaly, and mild abnormalities on laboratory tests. Three of them showed maturity-onset diabetes. The hyalin was found in the cytoplasm of swollen hepatocytes of the centrilobular or in the peripheral region of nodules and was accompanied by necrosis. Ultrastructurally, the hyalin comprised filamentous structures and vesicular or angular structures resembling disorganized circular or branched rough endoplasmic reticulum. It resembled that found in the liver of patients with alcoholic hepatitis.

References

  1. Am J Pathol. 1972 Oct;69(1):25-40 - PubMed
  2. Acta Med Scand. 1973 Dec;194(6):485-9 - PubMed
  3. Am J Med. 1979 Nov;67(5):811-6 - PubMed
  4. Lab Invest. 1964 Apr;13:301-20 - PubMed
  5. Gastroenterology. 1980 Mar;78(3):535-41 - PubMed
  6. Mayo Clin Proc. 1980 Jul;55(7):434-8 - PubMed
  7. Gastroenterology. 1971 Jun;60(6):1027-35 - PubMed
  8. Acta Hepatogastroenterol (Stuttg). 1979 Aug;26(4):296-301 - PubMed
  9. Acta Hepatogastroenterol (Stuttg). 1979 Apr;26(2):90-7 - PubMed

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