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Phillips PJ, Vedig AE, Jones PL, et al. Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol. Br J Clin Pharmacol. 1980;9(5):483-91doi: 10.1111/j.1365-2125.1980.tb05844.x.
Phillips, P. J., Vedig, A. E., Jones, P. L., Chapman, M. G., Collins, M., Edwards, J. B., Smeaton, T. C., & Duncan, B. M. (1980). Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol. British journal of clinical pharmacology, 9(5), 483-91. https://doi.org/10.1111/j.1365-2125.1980.tb05844.x
Phillips, P J, et al. "Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol." British journal of clinical pharmacology vol. 9,5 (1980): 483-91. doi: https://doi.org/10.1111/j.1365-2125.1980.tb05844.x
Phillips PJ, Vedig AE, Jones PL, Chapman MG, Collins M, Edwards JB, Smeaton TC, Duncan BM. Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol. Br J Clin Pharmacol. 1980 May;9(5):483-91. doi: 10.1111/j.1365-2125.1980.tb05844.x. PMID: 6104976; PMCID: PMC1429961.
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Wiley Free PMC Article

Br J Clin Pharmacol. 1980 May;9(5):483-91. doi: 10.1111/j.1365-2125.1980.tb05844.x.

Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol.

British journal of clinical pharmacology

P J Phillips, A E Vedig, P L Jones, M G Chapman, M Collins, J B Edwards, T C Smeaton, B M Duncan

PMID: 6104976 PMCID: PMC1429961 DOI: 10.1111/j.1365-2125.1980.tb05844.x
Free PMC Article

Abstract

The metabolic and cardiovascular side-effects of intravenous infusions of therapeutic doses of beta 2-adrenoceptor agonists salbutamol and rimiterol have been determined in four healthy male subjects. There were dose-related increases in plasma glucose, renin activity, serum insulin and heart rate, and significant hyperlactataemia and ketonaemia. There were dose-related decreases in plasma potassium, phosphate and corticosteroids and significant hypocalcaemia and hypomagnesaemia. The effects of equivalent molar amounts of salbutamol and rimiterol were similar. Whichever drug is used, special care is required with patients who may have abnormal glucose tolerance, potassium depletion, or be predisposed to lactic acidosis. Rimiterol may be preferable for infusion because of its short plasma half-life.

Cited by

Fainardi V, Caffarelli C, Bergamini BM, Biserna L, Bottau P, Corinaldesi E, Dondi A, Fornaro M, Guidi B, Lombardi F, Magistrali MS, Marastoni E, Piccorossi A, Poloni M, Tagliati S, Vaienti F, Venturelli C, Ricci G, Esposito S, On Behalf Of The Emilia-Romagna Asthma Era Study Group.
Int J Environ Res Public Health. 2021 Dec 03;18(23). doi: 10.3390/ijerph182312775.
PMID: 34886505

Fainardi V, Caffarelli C, Bergamini BM, Biserna L, Bottau P, Corinaldesi E, Dondi A, Fornaro M, Guidi B, Lombardi F, Magistrali MS, Marastoni E, Piccorossi A, Poloni M, Tagliati S, Vaienti F, Venturelli C, Ricci G, Esposito S, On Behalf Of The Emilia-Romagna Asthma Era Study Group.
Int J Environ Res Public Health. 2021 Dec 03;18(23). doi: 10.3390/ijerph182312775.
PMID: 34886505

Fainardi V, Caffarelli C, Bergamini BM, Biserna L, Bottau P, Corinaldesi E, Dondi A, Fornaro M, Guidi B, Lombardi F, Magistrali MS, Marastoni E, Piccorossi A, Poloni M, Tagliati S, Vaienti F, Venturelli C, Ricci G, Esposito S, On Behalf Of The Emilia-Romagna Asthma Era Study Group.
Int J Environ Res Public Health. 2021 Dec 03;18(23). doi: 10.3390/ijerph182312775.
PMID: 34886505

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