Acta Derm Venereol. 1982;62(5):431-4.

The chloroacetate esterase reaction for mast cells in dermatopathology: a comparison with metachromatic staining methods.

Acta dermato-venereologica

E Wong, E W Morgan, D M MacDonald

PMID: 6183895

Abstract

This paper compares standard metachromatic methods with Leder's chloroacetate esterase reaction on mast cells in paraffin wax-embedded tissue of urticaria pigmentosa and a variety of inflammatory and benign neoplastic cutaneous conditions. Our conclusions are that Leder's method allows easier identification of mast cells and can be a useful adjunct to conventional metachromatic methods. The technique could be conveniently adopted in routine dermatopathology for mast cell identification.

Substances

• Carboxylic Ester Hydrolases
• chloroacetate esterase

MeSH terms

• Carboxylic Ester Hydrolases*
• Histological Techniques
• Humans
• Mast Cells*
• Skin Diseases / diagnosis
• Staining and Labeling*
• Urticaria Pigmentosa / diagnosis

Publication Types

• Comparative Study
• Journal Article