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Hemming L, Burns C. Heterochromatic polymorphism in spontaneous abortions. J Med Genet. 1979;16(5):358-62doi: 10.1136/jmg.16.5.358.
Hemming, L., & Burns, C. (1979). Heterochromatic polymorphism in spontaneous abortions. Journal of medical genetics, 16(5), 358-62. https://doi.org/10.1136/jmg.16.5.358
Hemming, L, and Burns, C. "Heterochromatic polymorphism in spontaneous abortions." Journal of medical genetics vol. 16,5 (1979): 358-62. doi: https://doi.org/10.1136/jmg.16.5.358
Hemming L, Burns C. Heterochromatic polymorphism in spontaneous abortions. J Med Genet. 1979 Oct;16(5):358-62. doi: 10.1136/jmg.16.5.358. PMID: 513080; PMCID: PMC1012609.
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J Med Genet. 1979 Oct;16(5):358-62. doi: 10.1136/jmg.16.5.358.

Heterochromatic polymorphism in spontaneous abortions.

Journal of medical genetics

L Hemming, C Burns

PMID: 513080 PMCID: PMC1012609 DOI: 10.1136/jmg.16.5.358
Free PMC Article

Abstract

Since the advent of C-banding as a routine diagnostic procedure, the significance of heterochromatic polymorphism has been questioned. Some workers have considered variations in heterochromatin in chromosomes 1 and 9 to be associated with fetal wastage, recurrent abortions, and abnormal phenotypes. Over a 15-month period, this laboratory made a study of the diagnostic significance of heterochromatic variants in 50 couples with a history of recurrent abortions. A control group of 50 couples with at least two normal children and no miscarriages was investigated simultaneously. The results indicated no significant difference in the heterochromatic regions between aborting and non-aborting couples.

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