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Ann Plast Surg. 1979 Oct;3(4):361-7. doi: 10.1097/00000637-197910000-00012.

Cutaneous lymphoma masquerading as granuloma faciale.

Annals of plastic surgery

J M Noe, A H Sober, S H Fein, J H Grendell, H Sasken

PMID: 539766 DOI: 10.1097/00000637-197910000-00012

Abstract

Granuloma faciale is a presumably benign disorder of the skin--usually of the face--characterized by a dense, polymorphous, inflammatory infiltrate including numerous eosinophils, separated from the epidermis by a clear or "grenz" zone, and possessing a small vessel, leukocytoclastic vasculitis. Primary malignant lymphoma of the skin, other than mycosis fungoides, is an unusual entity that may follow a widely variable course and is often extremely difficult to diagnose definitively. A patient is presented in whom a lesion consistent with granuloma faciale changed its histological appearance and clinical behavior into that of a malignant lymphoma.

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