Display options
Cite
Peterson JE, King ME, Banks WF, et al. Radioimmunoassay for danazol in human and monkey plasma. J Pharm Sci. 1978;67(10):1425-8doi: 10.1002/jps.2600671026.
Peterson, J. E., King, M. E., Banks, W. F., Baker, J. F., Jensen, A. F., Ross, R. W., Clemans, S., & Edelson, J. (1978). Radioimmunoassay for danazol in human and monkey plasma. Journal of pharmaceutical sciences, 67(10), 1425-8. https://doi.org/10.1002/jps.2600671026
Peterson, J E, et al. "Radioimmunoassay for danazol in human and monkey plasma." Journal of pharmaceutical sciences vol. 67,10 (1978): 1425-8. doi: https://doi.org/10.1002/jps.2600671026
Peterson JE, King ME, Banks WF, Baker JF, Jensen AF, Ross RW, Clemans S, Edelson J. Radioimmunoassay for danazol in human and monkey plasma. J Pharm Sci. 1978 Oct;67(10):1425-8. doi: 10.1002/jps.2600671026. PMID: 100593.
Copy Download .nbib Format: NLM
Share it on
Full text links
Elsevier Science

J Pharm Sci. 1978 Oct;67(10):1425-8. doi: 10.1002/jps.2600671026.

Radioimmunoassay for danazol in human and monkey plasma.

Journal of pharmaceutical sciences

J E Peterson, M E King, W F Banks, J F Baker, A F Jensen, R W Ross, S Clemans, J Edelson

PMID: 100593 DOI: 10.1002/jps.2600671026

Abstract

A sensitive method is described for the radioimmunoassay of danazol in monkey and human plasma. Antiserum was developed in rabbits, and a second antibody was used to separate bound from free danazol. The radioimmunoassay was specific for danazol, and the limit of detection ranged from 1.4 to 2.8 ng/ml. Exogeneous danazol could be quantitated accurately in both monkey and human plasma. The radioimmunoassay results agreed with values obtained by inverse isotope dilution after intravenous administration of 14C-danazol to monkeys. The assay was used successfully to measure danazol in plasma from human volunteers receiving 200 mg of danazol.

Similar articles

Substances

MeSH terms

Publication Types

LinkOut - more resources