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Morphol Embryol (Bucur). 1975;21(3):211-2.

Aminoacetonitrile (AAN)prevents connective proliferation in rat liver induced by tetrachlorcarbon. Continuous concomitant administration of AAN.

E Repciuc, J Ciurea, V Ranga

PMID: 129695

Abstract

A total dose of 10 g/kg body weight of aminoacetonitrile distributed almost evenly over 35 days prevents formation of connective bands and damage of hepatocytes in the liver of rats submitted to CCl4 inhalations at a partial pressure of 1/6 atm, eight times within the same interaval. Control animals exhibited the usual pattern of CCl4 injury.

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