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Kunnen M, Devloo-Blancquaert A. Comparative study in angiocardiography in children, evaluating the side-effects of non-ionic and ionic contrast media. Diagn Imaging. 1979;48(4):228-34
Kunnen, M., & Devloo-Blancquaert, A. (1979). Comparative study in angiocardiography in children, evaluating the side-effects of non-ionic and ionic contrast media. Diagnostic imaging, 48(4), 228-34.
Kunnen, M, and Devloo-Blancquaert, A. "Comparative study in angiocardiography in children, evaluating the side-effects of non-ionic and ionic contrast media." Diagnostic imaging vol. 48,4 (1979): 228-34.
Kunnen M, Devloo-Blancquaert A. Comparative study in angiocardiography in children, evaluating the side-effects of non-ionic and ionic contrast media. Diagn Imaging. 1979;48(4):228-34. PMID: 498918.
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Diagn Imaging. 1979;48(4):228-34.

Comparative study in angiocardiography in children, evaluating the side-effects of non-ionic and ionic contrast media.

Diagnostic imaging

M Kunnen, A Devloo-Blancquaert

PMID: 498918

Abstract

The study concerns 127 consecutive patients, presenting congenital heart disease, with an age distribution from neonatal to 15 years (mean 5 years). With non-ionic Amipaque, 164 injections were performed, with ionic Isopaque Coronar 81. Isopaque Coronar caused in 51% of the cases a clear discomfort for the patient; with Amipaque the side-effects were reduced to 9% (p less than 0.001). The mean body temperature rise with Amipaque was only 0.09 degrees C, against 0.28 degrees C with Isopaque Coronar (p less than 0.001). The changes in the heart rate reached 8.35% with Amipaque and 15.2% with Isopaque Coronar (p less than 0.001). Amipaque caused a mean of 1.8 extrasystoles per injection; Isopaque Coronar 2.2 (p less than 0.05). The quality of the angiogram with Amipaque was quite better than with Isopaque Coronar (p less than 0.0025). The non-ionic Amipaque is a much safer and better tolerated compound that the ionic Isopaque Coronar for paediatric angiocardiography.

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