Display options
Share it on

Adv Exp Med Biol. 1979;120:451-9. doi: 10.1007/978-1-4757-0926-1_41.

Possible relationship between salivary kallikrein and water-Na-K secretion stimulated by tityustoxin (TsTx).

Advances in experimental medicine and biology

O L Catanzaro, A M Seeber, W T Beraldo

PMID: 495328 DOI: 10.1007/978-1-4757-0926-1_41

Abstract

Intravenous injection of purified scorpion toxin (TsTx) brings about the appearance of salivary flow with high levels of Na and K and kallikrein in the saliva of the rats. In experiments performed in vivo a positive correlation between Na and partially with K and kallikrein was observed in parotid and submaxillary saliva. After ouabaine, saliva K was increasing, whereas Na decreased, and a parallel decrease of kallikrein was observed. Adrenergic and cholinergic blocking drugs also showed a marked reduction in the output of Na (atropine), and partially of K (atropine or phentolamine), with a correlation in theoutput of kallikrein per min. The results of the present investigations support the hypothesis that salivary kallikrein-kinin system is probably involved in salivary control of Na, partially K and water secretion.

Similar articles

[No authors listed]
Hospital (Lond 1886). 1891 Jan 17;9(225):256-257.
PMID: 29821303

Substances

MeSH terms

Publication Types