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Arch Mal Coeur Vaiss. 1978 Jan;71(1):66-71.

[Vasodilator treatment of the acute phase of myocardial infarct with phentolamine. Analysis of hemodynamic results and therapeutic indications].

Archives des maladies du coeur et des vaisseaux

[Article in French]
M Francoual, D Lellouche, A Castaigne, B Estampes, N Benhaiem, P Vernant

PMID: 416775

Abstract

Treatment by phentolamine was carried out in 30 patients presenting with an acute myocardial infarction complicated by left ventricular failure, 8 of which had cardiogenic shock. The response to treatment was closely related to the level of overload of the left ventricle. Significant improvement in the haemodynamic state was only observed in the most severe cases of cardiac failure, and in these cases was accompanied by only a minimal and insignificant change in mean arterial pressure and heart rate.

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