Biokhimiia. 1985 Nov;50(11):1853-8.

[Comparative analysis of the interaction of various estrogens with the estrogen-receptor system of the uterus].

Biokhimiia (Moscow, Russia)

[Article in Russian]
N D Fanchenko, M L Alekseeva, L S Minina, E A Novikov, D K Khel'mun

PMID: 4063405

Abstract

Equilibrium binding of labeled estron, estradiol, estriol and DES was studied in uterine cytosol of immature Wistar rats. The dissociation kinetics of the ligand complexes with specific high affinity sites suggested the homogeneity of estrogen receptors in rat uterine cytosol. The feasibility of intracellular regulation of estrogen action in target cells both at the receptor and post-receptor levels is discussed.

Substances

• Estrogens
• Receptors, Estrogen
• Estrone
• Estradiol
• Estriol

MeSH terms

• Animals
• Cytosol / metabolism
• Estradiol / metabolism
• Estriol / metabolism
• Estrogens / metabolism
• Estrone / metabolism
• Female
• In Vitro Techniques
• Kinetics
• Rats
• Rats, Inbred Strains
• Receptors, Estrogen / metabolism
• Uterus / metabolism

Publication Types

• Comparative Study
• English Abstract
• Journal Article