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Kardiologiia. 1985 Sep;25(9):45-8.

[Synergism of the anti-anginal action of beta-blockers and calcium antagonists in patients with ischemic heart disease].

Kardiologiia

[Article in Russian]
N A Mazur, A B Sumarokov, A M Sagirov

PMID: 3935847

Abstract

A variety of anti-anginal drugs and their combinations were selected in a group of patients with stable angina of effort, with the effects assessed by bicycle ergometry. Effective doses of propranolol, corinfar, finoptin provided for at least 3 minutes' increment in the duration of the effort. Combinations of these drugs in doses reduced by half produced a more pronounced increment in the duration of the effort, an observation suggestive of synergistic anti-anginal effects of calcium antagonists and beta-blockers.

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