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Minerva Med. 1985 Oct 27;76(41):1921-6.

[Monoclonal gammopathies: classification of laboratory tests].

Minerva medica

[Article in Italian]
G D'Angelo, C Giardini, D Calvano, T Braghini

PMID: 3932901

Abstract

Monoclonal gammopathies have been examined and classified. In the field of chemico-clinical and immunological investigations, the various methods of analysing dysproteinaemia, of which the monoclonal component is a typical expression (electrophoresis, radial immunodiffusion, immunoelectrophoresis, immunofixation), and the main haematological and immunohaematological changes (lymphocyte biological markers) involved are reviewed. After describing the main histological and histo-cytochemical investigations, particularly amyloidosis, electronic microscope aspects and the most important chromosome abnormalities revealed by karyotype study are reported for their diagnostic interest.

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