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Gan To Kagaku Ryoho. 1986 Apr;13(4):1366-71.

[Electrocardiographic and hemodynamic changes during systemic hyperthermia (42 degrees C)].

Gan to kagaku ryoho. Cancer & chemotherapy

[Article in Japanese]
M Yokoyama, J Wada, H Nakajima, M Saitoh

PMID: 3729456

Abstract

During systemic hyperthermia (42 degrees C), depression of ST segments or T wave changes in the left precordial leads were noticed in 56% of patients, and 29% of cases showed right bundle branch block. Supraventricular tachycardia was found in 26% and temporary deviation of mean frontal vector to the left axis was observed in 15%. These changes disappeared following recovery to normal temperature. The ECG findings for any particular patient were similar even during a second period of hyperthermia. Pulse rate became elevated by 1.7 times, and cardiac output became up to 2.4 times higher at 42 degrees C.

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