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Radiobiologiia. 1986 Nov-Dec;26(6):842-4.

[Effect of metronidazole on the free thymidine content in the blood serum of irradiated mice].

Radiobiologiia

[Article in Russian]
A V Konov, N I Riabchenko

PMID: 3809422

Abstract

The influence of a radiosensitizer, metronidazole, on the free thymidine content of blood serum of irradiated mice was studied in aerobic and hypoxic conditions. A heated metronidazole solution (1 mg/g) was administered intraperitoneally 30 min before irradiation of animals with a dose of 3 Gy. Thymidine concentration in blood serum was determined by the radioimmunological technique. The influence of metronidazole on the level of thymidinemia was only noted in the animals exposed under hypoxic conditions.

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