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Montani E, Candotti C, Triulzi MO, et al. Valutazione funzionale della regolazione neurovegetativa nel prolasso valvolare mitralico. [Functional evaluation of the autonomic regulation in mitral valve prolapse]. G Ital Cardiol. 1986;16(11):934-40
Montani, E., Candotti, C., Triulzi, M. O., Modesti, R., & Maggi, G. C. (1986). Valutazione funzionale della regolazione neurovegetativa nel prolasso valvolare mitralico. [Functional evaluation of the autonomic regulation in mitral valve prolapse]. Giornale italiano di cardiologia, 16(11), 934-40.
Montani, E, et al. "Valutazione funzionale della regolazione neurovegetativa nel prolasso valvolare mitralico." [Functional evaluation of the autonomic regulation in mitral valve prolapse]. Giornale italiano di cardiologia vol. 16,11 (1986): 934-40.
Montani E, Candotti C, Triulzi MO, Modesti R, Maggi GC. Valutazione funzionale della regolazione neurovegetativa nel prolasso valvolare mitralico. [Functional evaluation of the autonomic regulation in mitral valve prolapse]. G Ital Cardiol. 1986 Nov;16(11):934-40. Italian. PMID: 3556930.
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G Ital Cardiol. 1986 Nov;16(11):934-40.

[Functional evaluation of the autonomic regulation in mitral valve prolapse].

Giornale italiano di cardiologia

[Article in Italian]
E Montani, C Candotti, M O Triulzi, R Modesti, G C Maggi

PMID: 3556930

Abstract

We examined fifty patients aged from 15 to 35 years, mean 23 +/- 5, with mitral valve prolapse (MVP) documented by two-dimensional echocardiography in the apical 4-chamber view as well as in the parasternal-long axis. The patients have been submitted to 4 tests: Valsalva maneuver, standing and exercise test and 24 hours ambulatory ECG monitoring. Fourty-five healthy subjects of similar age and sex served as controls. During the standing test the patients with MVP showed a significantly faster heart rate than the control subjects both in resting and in the standing position; during the exercise test they exhibited higher prevalence of ST segment and T wave abnormalities disappearing at the peak of the exercise. These observations support the hypothesis of a hyperadrenergic state. The greater bradycardia showed during the Valsalva maneuver, the lower heart rate and the higher incidence of bradyarrhythmias and A-V blocks during the sleeping period suggest an increased vagal tone. Our results suggest therefore that in subjects with MVP a dysfunction of both, sympathetic and parasympathetic nervous system is present.

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