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Taylor NE, Baker SE, Olson TP, et al. Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans. Clin Med Insights Circ Respir Pulm Med. 2016;10:19-25doi: 10.4137/CCRPM.S30251.
Taylor, N. E., Baker, S. E., Olson, T. P., Lalande, S., Johnson, B. D., & Snyder, E. M. (2016). Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans. Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 1019-25. https://doi.org/10.4137/CCRPM.S30251
Taylor, Natalie E, et al. "Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans." Clinical medicine insights. Circulatory, respiratory and pulmonary medicine vol. 10 (2016): 19-25. doi: https://doi.org/10.4137/CCRPM.S30251
Taylor NE, Baker SE, Olson TP, Lalande S, Johnson BD, Snyder EM. Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans. Clin Med Insights Circ Respir Pulm Med. 2016 Oct 12;10:19-25. doi: 10.4137/CCRPM.S30251. eCollection 2016. PMID: 27773996; PMCID: PMC5063752.
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Clin Med Insights Circ Respir Pulm Med. 2016 Oct 12;10:19-25. doi: 10.4137/CCRPM.S30251. eCollection 2016.

Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans.

Clinical medicine insights. Circulatory, respiratory and pulmonary medicine

Natalie E Taylor, Sarah E Baker, Thomas P Olson, Sophie Lalande, Bruce D Johnson, Eric M Snyder

Affiliations

  1. School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
  2. Research Fellow, Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA.
  3. Assistant Professor of Medicine, Consultant, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  4. Assistant Professor, Department of Kinesiology, University of Toledo, OH, USA.
  5. Professor of Medicine and Physiology, Consultant, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  6. Assistant Professor, School of Kinesiology, University of Minnesota, Minneapolis, MN, USA.

PMID: 27773996 PMCID: PMC5063752 DOI: 10.4137/CCRPM.S30251

Abstract

BACKGROUND: Beta-2 adrenergic receptors (β

METHODS: We assessed the diffusing capacity of the lungs for carbon monoxide (DLCO) and nitric oxide (DLNO) at baseline, 30 minutes, and 60 minutes following nebulized albuterol (2.5 mg, diluted in 3 mL normal saline) in 45 healthy subjects. Seventeen subjects repeated these measures following nebulized normal saline (age = 27 ± 9 years, height = 165 ± 21 cm, weight = 68 ± 12 kg, BMI = 26 ± 9 kg/m

RESULTS: Albuterol resulted in a decrease in SVR, and an increase in Q, FEV

CONCLUSION: These data suggest that nebulized albuterol improves pulmonary function in healthy humans, while nebulization of both albuterol and saline results in an increase in DM/

Keywords: CFTR; lung diffusion; lung fluid; sodium channels

Conflict of interest statement

Authors disclose no potential conflicts of interest.

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