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Shah PS, Hakak H, Mohamed A, et al. Oxygen saturation profile in late-preterm and term infants: a prospective cohort study. J Perinatol. 2014;34(12):917-20doi: 10.1038/jp.2014.107.
Shah, P. S., Hakak, H., Mohamed, A., Shah, J., Young, J., & Kelly, E. (2014). Oxygen saturation profile in late-preterm and term infants: a prospective cohort study. Journal of perinatology : official journal of the California Perinatal Association, 34(12), 917-20. https://doi.org/10.1038/jp.2014.107
Shah, P S, et al. "Oxygen saturation profile in late-preterm and term infants: a prospective cohort study." Journal of perinatology : official journal of the California Perinatal Association vol. 34,12 (2014): 917-20. doi: https://doi.org/10.1038/jp.2014.107
Shah PS, Hakak H, Mohamed A, Shah J, Young J, Kelly E. Oxygen saturation profile in late-preterm and term infants: a prospective cohort study. J Perinatol. 2014 Dec;34(12):917-20. doi: 10.1038/jp.2014.107. Epub 2014 Jun 05. PMID: 24901450.
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J Perinatol. 2014 Dec;34(12):917-20. doi: 10.1038/jp.2014.107. Epub 2014 Jun 05.

Oxygen saturation profile in late-preterm and term infants: a prospective cohort study.

Journal of perinatology : official journal of the California Perinatal Association

P S Shah, H Hakak, A Mohamed, J Shah, J Young, E Kelly

Affiliations

  1. Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

PMID: 24901450 DOI: 10.1038/jp.2014.107

Abstract

OBJECTIVE: To determine oxygen saturation profile over 6 h monitoring period in healthy late-preterm and term neonates during the first 48 h of age, and to assess the impact of gestational age, birth weight and method of delivery on this profile.

STUDY DESIGN: Prospective cohort study of measurement of SpO2 over 6 h in 20 late-preterm (35 to 36 weeks gestation) and 40 term infants within 12 to 48 h of birth was conducted. Infants with cardiorespiratory symptoms or need for cardiorespiratory support at birth were excluded. Percentage time spent at SpO2 >90% and ⩽90% was calculated by gestational age and birth weight.

RESULT: Late-preterm infants and infants born weighing <2.5 kg spent approximately 7% of the time at SpO2 ⩽90%; this time decreased as gestational age and birth weight increased. Time at SpO2 >90% was significantly different between late-preterm and term infants (93% (5%) vs 96% (3%); P =0.002). Time at SpO2 >90% was not significantly different between males and females (95% (5%) vs 95% (4%), both n=30; P =0.72) or between vaginal births and cesarean births (95% (4%), n=32, vs 95% (4%), n=28; P =0.39). Cumulative time with SpO2 <90 was mean (s.d.) of 25 (18) in preterm vs 13 (10) min in term infants.

CONCLUSION: Over a 6-h period healthy late-preterm and term infants spent significant time at SpO2 ⩽90%. Lower gestation and lower birth weight were associated with higher time at SpO2 ⩽90%.

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