Display options
Cite
Schulman SP, Achuff SC, Griffith LS, et al. Prognostic cardiac catheterization variables in survivors of acute myocardial infarction: a five year prospective study. J Am Coll Cardiol. 1988;11(6):1164-72doi: 10.1016/0735-1097(88)90277-x.
Schulman, S. P., Achuff, S. C., Griffith, L. S., Humphries, J. O., Taylor, G. J., Mellits, E. D., Kennedy, M., Baumgartner, R., Weisfeldt, M. L., & Baughman, K. L. (1988). Prognostic cardiac catheterization variables in survivors of acute myocardial infarction: a five year prospective study. Journal of the American College of Cardiology, 11(6), 1164-72. https://doi.org/10.1016/0735-1097(88)90277-x
Schulman, S P, et al. "Prognostic cardiac catheterization variables in survivors of acute myocardial infarction: a five year prospective study." Journal of the American College of Cardiology vol. 11,6 (1988): 1164-72. doi: https://doi.org/10.1016/0735-1097(88)90277-x
Schulman SP, Achuff SC, Griffith LS, Humphries JO, Taylor GJ, Mellits ED, Kennedy M, Baumgartner R, Weisfeldt ML, Baughman KL. Prognostic cardiac catheterization variables in survivors of acute myocardial infarction: a five year prospective study. J Am Coll Cardiol. 1988 Jun;11(6):1164-72. doi: 10.1016/0735-1097(88)90277-x. PMID: 3366994.
Copy Download .nbib Format: NLM
Share it on
Full text links
Elsevier Science

J Am Coll Cardiol. 1988 Jun;11(6):1164-72. doi: 10.1016/0735-1097(88)90277-x.

Prognostic cardiac catheterization variables in survivors of acute myocardial infarction: a five year prospective study.

Journal of the American College of Cardiology

S P Schulman, S C Achuff, L S Griffith, J O Humphries, G J Taylor, E D Mellits, M Kennedy, R Baumgartner, M L Weisfeldt, K L Baughman

Affiliations

  1. Divison of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

PMID: 3366994 DOI: 10.1016/0735-1097(88)90277-x
Free Article

Abstract

The prognostic variables from predischarge coronary angiography and left ventriculography in survivors of acute myocardial infarction during the years 1974 to 1978 were evaluated in 143 patients (less than or equal to 66 years of age) with documented myocardial infarction who were then followed up prospectively for 5 years. One half of the study population had triple vessel coronary disease (greater than or equal to 50% stenosis). However, only 7% of patients had severely depressed left ventricular function with an ejection fraction less than or equal to 29%. Evaluation of the contribution of many clinical and angiographic variables to a first cardiac event (death, nonfatal reinfarction or coronary artery bypass surgery) was considered with Kaplan-Meier actuarial curves and multivariate Cox's hazard function analysis. A risk segment was defined as an area of contracting myocardium supplied by a coronary artery with a greater than 50% stenosis. Multivariate analysis demonstrated that right plus left anterior descending coronary artery stenoses (p less than 0.01), ejection fraction (p less than 0.01) and the presence of risk segments (p less than 0.05) were significant predictors of outcome. Furthermore, on separate multivariate analyses, the angiographic variables added significantly to the clinical variables to predict cardiac events over 5 years of follow-up. Therefore, in survivors of acute myocardial infarction who undergo cardiac catheterization, additive prognostic information is obtained that can be used to stratify risk over 5 years.

Similar articles

MeSH terms

Publication Types

Grant support

LinkOut - more resources