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Tissue Antigens. 1988 Sep;32(3):170-5. doi: 10.1111/j.1399-0039.1988.tb01654.x.

Erythema multiforme is associated to HLA-Aw33 and DRw53.

Tissue antigens

V Lepage, C Douay, C Mallet, O Binet, F Lemarchand, D Wallach, M Masset, J Colombani, L Degos

Affiliations

  1. Laboratoire d'Immunologie et d'Histocompatibilité, Hôpital Saint Louis, France.

PMID: 3217933 DOI: 10.1111/j.1399-0039.1988.tb01654.x

Abstract

Erythema multiforme is an acute eruption of the skin and mucous membranes of various aetiologies. Forty-one unrelated patients were HLA typed for 53 specificities of the HLA-A, B, C, DR and DQ series. Frequencies of Aw33 and DRw53 were significantly increased: Aw33, 17.0% in patients vs 2.8% in controls (corrected p = 0.01, relative risk = 7.2); DRw53, 70.7% in patients vs 30.5% in controls (corrected p = 0.0005, relative risk = 5.5).

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