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Hermann RC, Ellis CN, Fitting DW, et al. Measurement of epidermal thickness in normal skin and psoriasis with high-frequency ultrasound. Skin Pharmacol. 1988;1(2):128-36doi: 10.1159/000210760.
Hermann, R. C., Ellis, C. N., Fitting, D. W., Ho, V. C., & Voorhees, J. J. (1988). Measurement of epidermal thickness in normal skin and psoriasis with high-frequency ultrasound. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1(2), 128-36. https://doi.org/10.1159/000210760
Hermann, R C, et al. "Measurement of epidermal thickness in normal skin and psoriasis with high-frequency ultrasound." Skin pharmacology : the official journal of the Skin Pharmacology Society vol. 1,2 (1988): 128-36. doi: https://doi.org/10.1159/000210760
Hermann RC, Ellis CN, Fitting DW, Ho VC, Voorhees JJ. Measurement of epidermal thickness in normal skin and psoriasis with high-frequency ultrasound. Skin Pharmacol. 1988;1(2):128-36. doi: 10.1159/000210760. PMID: 3273201.
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Skin Pharmacol. 1988;1(2):128-36. doi: 10.1159/000210760.

Measurement of epidermal thickness in normal skin and psoriasis with high-frequency ultrasound.

Skin pharmacology : the official journal of the Skin Pharmacology Society

R C Hermann, C N Ellis, D W Fitting, V C Ho, J J Voorhees

Affiliations

  1. Department of Dermatology, University of Michigan Medical Center, Ann Arbor.

PMID: 3273201 DOI: 10.1159/000210760

Abstract

In this study, we employed a high-frequency ultrasound system to measure the epidermal thicknesses of psoriasis plaques and normal skin in vivo. Eighty-four percent of the ultrasound measurements fell within the range of epidermal thickness determined by histology. The average thickness of untreated psoriasis measured by ultrasound was significantly greater than that of either treated psoriasis or normal skin. Ultrasound measurement of thickness was consistent with clinical assessment. Ultrasound measurements also demonstrated known variations in epidermal thickness by body site. Further development is needed to obtain measurements that are fully representative of the epidermis.

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