Display options
Cite
Jung S, Bosch A, Kolwelter J, et al. Renal and intraglomerular haemodynamics in chronic heart failure with preserved and reduced ejection fraction. ESC Heart Fail. 2021;8(2):1562-1570doi: 10.1002/ehf2.13257.
Jung, S., Bosch, A., Kolwelter, J., Striepe, K., Kannenkeril, D., Schuster, T., Ott, C., Achenbach, S., & Schmieder, R. E. (2021). Renal and intraglomerular haemodynamics in chronic heart failure with preserved and reduced ejection fraction. ESC heart failure, 8(2), 1562-1570. https://doi.org/10.1002/ehf2.13257
Jung, Susanne, et al. "Renal and intraglomerular haemodynamics in chronic heart failure with preserved and reduced ejection fraction." ESC heart failure vol. 8,2 (2021): 1562-1570. doi: https://doi.org/10.1002/ehf2.13257
Jung S, Bosch A, Kolwelter J, Striepe K, Kannenkeril D, Schuster T, Ott C, Achenbach S, Schmieder RE. Renal and intraglomerular haemodynamics in chronic heart failure with preserved and reduced ejection fraction. ESC Heart Fail. 2021 Apr;8(2):1562-1570. doi: 10.1002/ehf2.13257. Epub 2021 Feb 09. PMID: 33559346; PMCID: PMC8006684.
Copy Download .nbib Format: NLM
Share it on

ESC Heart Fail. 2021 Apr;8(2):1562-1570. doi: 10.1002/ehf2.13257. Epub 2021 Feb 09.

Renal and intraglomerular haemodynamics in chronic heart failure with preserved and reduced ejection fraction.

ESC heart failure

Susanne Jung, Agnes Bosch, Julie Kolwelter, Kristina Striepe, Dennis Kannenkeril, Tizia Schuster, Christian Ott, Stephan Achenbach, Roland E Schmieder

Affiliations

  1. Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich-Alexander-University, Ulmenweg 18, Erlangen-Nuremberg, 91054, Germany.
  2. Department of Cardiology and Angiology, University Hospital Erlangen, Friedrich-Alexander-University, Erlangen-Nuremberg, Germany.
  3. Paracelsus Medical School Nuremberg, Nuremberg, Germany.

PMID: 33559346 PMCID: PMC8006684 DOI: 10.1002/ehf2.13257

Abstract

AIMS: Congestive heart failure (CHF) and impaired renal function are two often co-existing medical conditions and associated with adverse cardiovascular outcome. The aim of the current study was to assess renal and intraglomerular haemodynamics by constant infusion input clearance technique in subjects with CHF.

METHODS AND RESULTS: The group of subjects with CHF consisted of 27 individuals with HFpEF and 27 individuals with HFrEF and were compared with 31 healthy controls. Subjects underwent renal clearance examination to measure glomerular filtration rate (GFR) and renal blood and plasma flow (RBF and RPF) and to calculate intraglomerular haemodynamics such as resistances of the afferent (R

CONCLUSIONS: Renal function assessed by measured GFR is reduced and renal vascular resistance at the preglomerular, afferent site is increased in HFpEF and, to greater extent, in HFrEF. Our data indicate a close cardiorenal interaction in CHF.

© 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

Keywords: Cardiorenal interaction; Heart failure; Preserved ejection fraction; Reduced ejection fraction; Renal haemodynamics

References

  1. Int J Nephrol. 2010 Oct 04;2011:283137 - PubMed
  2. Circ Res. 1974 Mar;34(3):309-16 - PubMed
  3. Circulation. 2006 Feb 7;113(5):671-8 - PubMed
  4. Eur Heart J. 2016 Jul 14;37(27):2129-2200 - PubMed
  5. Eur J Heart Fail. 2015 May;17(5):510-7 - PubMed
  6. J Renin Angiotensin Aldosterone Syst. 2013 Sep;14(3):193-6 - PubMed
  7. Eur J Heart Fail. 2016 Jun;18(6):588-98 - PubMed
  8. JACC Heart Fail. 2018 Jun;6(6):489-498 - PubMed
  9. J Am Coll Cardiol. 2006 Oct 17;48(8):1621-7 - PubMed
  10. Eur Heart J. 2014 Feb;35(7):416-8 - PubMed
  11. J Am Coll Cardiol. 2001 Oct;38(4):955-62 - PubMed
  12. Eur J Heart Fail. 2016 Jan;18(1):103-12 - PubMed
  13. Am J Hypertens. 2003 Dec;16(12):1030-5 - PubMed
  14. Prog Cardiovasc Dis. 2011 Sep-Oct;54(2):144-53 - PubMed
  15. Am J Cardiol. 2007 Feb 1;99(3):393-8 - PubMed
  16. J Am Coll Cardiol. 2009 Feb 17;53(7):582-588 - PubMed
  17. Am J Physiol. 1994 Jul;267(1 Pt 2):F35-43 - PubMed
  18. Eur Heart J. 2014 Dec 21;35(48):3442-51 - PubMed
  19. J Am Soc Nephrol. 1997 Jun;8(6):893-900 - PubMed
  20. Eur Heart J. 2014 Feb;35(7):455-69 - PubMed
  21. Crit Care Med. 2018 Mar;46(3):e190-e197 - PubMed
  22. ESC Heart Fail. 2021 Apr;8(2):1562-1570 - PubMed
  23. Kidney Int. 2014 Mar;85(3):487-91 - PubMed
  24. Clin Sci (Lond). 2014 Oct;127(7):499-505 - PubMed
  25. Clin Kidney J. 2016 Oct;9(5):682-99 - PubMed
  26. Br J Clin Pharmacol. 2013 Jan;75(1):129-35 - PubMed
  27. Cardiology. 2013;126(3):175-86 - PubMed
  28. Adv Chronic Kidney Dis. 2010 Jul;17(4):302-7 - PubMed
  29. Eur Heart J. 2006 Mar;27(5):569-81 - PubMed
  30. J Transl Med. 2015 Feb 12;13:58 - PubMed
  31. Circulation. 2000 Jul 11;102(2):203-10 - PubMed
  32. Circulation. 2004 Mar 2;109(8):1004-9 - PubMed
  33. Clin Kidney J. 2016 Oct;9(5):700-4 - PubMed
  34. Eur Heart J. 2013 May;34(19):1424-31 - PubMed
  35. Eur Heart J. 2018 Sep 1;39(33):3021-3104 - PubMed
  36. J Am Coll Cardiol. 2002 Sep 18;40(6):1106-13 - PubMed
  37. Eur J Heart Fail. 2000 Sep;2(3):229-33 - PubMed
  38. Am J Cardiol. 1991 May 6;67(12):3C-5C - PubMed
  39. Eur Heart J. 2012 Sep;33(17):2135-42 - PubMed
  40. J Clin Invest. 1951 Oct;30(10):1143-55 - PubMed
  41. J Clin Invest. 1950 May;29(5):496-507 - PubMed
  42. Atherosclerosis. 2008 Feb;196(2):704-11 - PubMed
  43. J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):6A-13A - PubMed

MeSH terms

Publication Types