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Somat Cell Mol Genet. 1986 Jul;12(4):395-401. doi: 10.1007/BF01570734.

Mapping of human autosomal phosphoglycerate kinase sequence to chromosome 19.

Somatic cell and molecular genetics

S M Gartler, D E Riley, R V Lebo, M C Cheung, R L Eddy, T B Shows

PMID: 3016919 DOI: 10.1007/BF01570734

Abstract

In order to map human PGK sequences, DNA was prepared from 55 human-mouse somatic cell lines. The DNA was digested to completion with HindIII and Southern filters prepared. These filters were hybridized at high stringency conditions to a human PGK cDNA. Mouse and human X-linked and autosomal bands were distinguished and, in addition to known X-linked sequences, two autosomal PGK sequences were mapped: a 1-kb band to chromosome 19 and a 5-kb band to chromosome 6. The PGK cDNA probe was also hybridized to flow-sorted chromosomes confirming the presence of PGK sequences on the X chromosome and chromosomes 6 and 19.

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