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Mango D, Scirpa P, Battaglia F, et al. A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels. J Endocrinol Invest. 1985;8(4):359-62doi: 10.1007/BF03348514.
Mango, D., Scirpa, P., Battaglia, F., Sentinelli, S., & Menini, E. (1985). A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels. Journal of endocrinological investigation, 8(4), 359-62. https://doi.org/10.1007/BF03348514
Mango, D, et al. "A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels." Journal of endocrinological investigation vol. 8,4 (1985): 359-62. doi: https://doi.org/10.1007/BF03348514
Mango D, Scirpa P, Battaglia F, Sentinelli S, Menini E. A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels. J Endocrinol Invest. 1985 Aug;8(4):359-62. doi: 10.1007/BF03348514. PMID: 2933445.
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J Endocrinol Invest. 1985 Aug;8(4):359-62. doi: 10.1007/BF03348514.

A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels.

Journal of endocrinological investigation

D Mango, P Scirpa, F Battaglia, S Sentinelli, E Menini

PMID: 2933445 DOI: 10.1007/BF03348514

Abstract

A premenopausal woman with a mucinous carcinoma of one ovary, and a mucinous adenoma of the other, together with secondary virilization, is reported. Preoperative levels of androstenedione, testosterone and dehydroepiandrosterone sulphate were high, suggesting the presence of a virilizing tumor. Preoperative plasma estrone (E1), but not estradiol (E2), was elevated along with inversion of the E2/E1 ratio, suggesting a peripheral origin of the estrogens. FSH and LH plasma concentrations were low. After bilateral ovariectomy, levels of all steroids measured significantly decreased and gonadotropins rose to the postmenopausal range.

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