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Qualman SJ, Green WR, Brovall C, et al. Neurofibromatosis and associated neuroectodermal tumors: a congenital neurocristopathy. Pediatr Pathol. 1986;5(1):65-78doi: 10.3109/15513818609068849.
Qualman, S. J., Green, W. R., Brovall, C., & Leventhal, B. G. (1986). Neurofibromatosis and associated neuroectodermal tumors: a congenital neurocristopathy. Pediatric pathology, 5(1), 65-78. https://doi.org/10.3109/15513818609068849
Qualman, S J, et al. "Neurofibromatosis and associated neuroectodermal tumors: a congenital neurocristopathy." Pediatric pathology vol. 5,1 (1986): 65-78. doi: https://doi.org/10.3109/15513818609068849
Qualman SJ, Green WR, Brovall C, Leventhal BG. Neurofibromatosis and associated neuroectodermal tumors: a congenital neurocristopathy. Pediatr Pathol. 1986;5(1):65-78. doi: 10.3109/15513818609068849. PMID: 3014462.
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Pediatr Pathol. 1986;5(1):65-78. doi: 10.3109/15513818609068849.

Neurofibromatosis and associated neuroectodermal tumors: a congenital neurocristopathy.

Pediatric pathology

S J Qualman, W R Green, C Brovall, B G Leventhal

PMID: 3014462 DOI: 10.3109/15513818609068849

Abstract

The synchronous occurrence of neurofibromatosis and neuroblastoma has been labeled in the recent literature as a chance event. We report 2 cases of newborn infants with congenital neurofibromatosis and a similar midline pattern of multiple Schwann cell and neuroblastic tumors; other types of ectomesenchymal tumor differentiation are documented, along with supportive ultrastructural and immunohistochemical studies. The tumors may take an aggressive, fatal course despite maximal multimodality antitumor therapy. These 2 cases are reported, with additional literature review, to document a clinically recognizable neurocristopathy that links neuroblastic tumors and neurofibromatosis.

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