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Shanbhag SS, Chodosh J, Fathy C, et al. Multidisciplinary care in Stevens-Johnson syndrome. Ther Adv Chronic Dis. 2020;11:2040622319894469doi: 10.1177/2040622319894469.
Shanbhag, S. S., Chodosh, J., Fathy, C., Goverman, J., Mitchell, C., & Saeed, H. N. (2020). Multidisciplinary care in Stevens-Johnson syndrome. Therapeutic advances in chronic disease, 112040622319894469. https://doi.org/10.1177/2040622319894469
Shanbhag, Swapna S, et al. "Multidisciplinary care in Stevens-Johnson syndrome." Therapeutic advances in chronic disease vol. 11 (2020): 2040622319894469. doi: https://doi.org/10.1177/2040622319894469
Shanbhag SS, Chodosh J, Fathy C, Goverman J, Mitchell C, Saeed HN. Multidisciplinary care in Stevens-Johnson syndrome. Ther Adv Chronic Dis. 2020 Apr 28;11:2040622319894469. doi: 10.1177/2040622319894469. eCollection 2020. PMID: 32523661; PMCID: PMC7236394.
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Ther Adv Chronic Dis. 2020 Apr 28;11:2040622319894469. doi: 10.1177/2040622319894469. eCollection 2020.

Multidisciplinary care in Stevens-Johnson syndrome.

Therapeutic advances in chronic disease

Swapna S Shanbhag, James Chodosh, Cherie Fathy, Jeremy Goverman, Caroline Mitchell, Hajirah N Saeed

Affiliations

  1. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
  2. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  3. Department of Surgery, Massachusetts General Hospital, Sumner Redstone Burn Center, Boston, MA, USA.
  4. Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.
  5. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA.

PMID: 32523661 PMCID: PMC7236394 DOI: 10.1177/2040622319894469

Abstract

Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are potentially fatal mucocutaneous diseases that can involve many organ systems. Manifestations of SJS/TEN outside of the skin, eyes, and oral mucosa are not well defined or well recognized, and, therefore, are often not addressed clinically. As supportive care improves and mortality from SJS/TEN decreases, chronic complications in affected organ systems are becoming more prevalent. Recognition of the manifestations of SJS/TEN in the acute phase is critical to optimal care. In this review, we review the organ systems that may be involved in SJS/TEN, provide an overview of their management, and propose a list of items that should be communicated to the patient and family upon discharge. The organ systems discussed include the pulmonary, gastrointestinal/hepatic, oral, otorhinolaryngologic, gynecologic, genitourinary, and renal systems. In addition, the significant psychosocial, nutritional, and pain consequences and management of SJS/TEN are discussed.

© The Author(s), 2020.

Keywords: Stevens-Johnson syndrome; burns; complications; gastrointestinal; gynecologic; ocular; pulmonary; toxic epidermal necrolysis

Conflict of interest statement

Conflict of interest statement: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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