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Arch Neurol. 1988 Jun;45(6):693-7. doi: 10.1001/archneur.1988.00520300113031.

A direct electron microscopic immunocytochemical study of IgM paraproteinemic neuropathy.

Archives of neurology

M Mata, S N Kahn, D J Fink

Affiliations

  1. Department of Neurology, Veterans Administration Medical Center, Ann Arbor, MI 48105.

PMID: 2835954 DOI: 10.1001/archneur.1988.00520300113031

Abstract

Direct electron microscopic immunohistochemistry of the sural nerve of a patient with neuropathy and an IgMk paraprotein demonstrated that immunoglobulin was deposited throughout the compact myelin. These findings support the notion that immunoglobulin deposition plays a role in the pathogenesis of the neuropathy in vivo.

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