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Am J Gastroenterol. 1989 Apr;84(4):426-8.

Danazol-induced cholestasis.

The American journal of gastroenterology

M O Silva, K R Reddy, T McDonald, L J Jeffers, E R Schiff

Affiliations

  1. Center for Liver Diseases, University of Miami School of Medicine, VA Medical Center, Florida.

PMID: 2929566

Abstract

A 39-yr-old female on high-dose Danazol presented with jaundice and pruritus. Danazol-induced cholestasis was suspected, and the drug was discontinued. A liver biopsy revealed panlobular cholestasis with portal and periportal inflammation. The cholestasis resolved completely in 8 wk. This is a rare case of Danazol-induced cholestasis and should be considered in the differential diagnosis of drug-induced liver injury.

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