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Biomolecules. 2020 Apr 29;10(5). doi: 10.3390/biom10050688.

Functional Implications of Cathelicidin Antimicrobial Protein in Breast Cancer and Tumor-Associated Macrophage Microenvironment.

Biomolecules

Jiawei Chen, Vivian Yvonne Shin, John Chi-Wang Ho, Man-Ting Siu, Isabella Wai-Yin Cheuk, Ava Kwong

Affiliations

  1. Department of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
  2. Department of Surgery, The Hong Kong Sanatorium and Hospital, Wan Chai District 999077, Hong Kong.
  3. The Hong Kong Hereditary Breast Cancer Family Registry, Shatin 999077, Hong Kong.

PMID: 32365569 PMCID: PMC7277779 DOI: 10.3390/biom10050688

Abstract

It is well-established that tumor-associated macrophages (TAMs) play an important role in breast cancer development. Accumulating evidence suggested that human cathelicidin antimicrobial protein (

Keywords: breast cancer; cathelicidin antimicrobia; tumor associated macrophage; tumor microenvironment

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