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de Silva M, Contreras M, Mollison PL. Failure of passively administered anti-Rh to prevent secondary Rh responses. Vox Sang. 1985;48(3):178-80doi: 10.1111/j.1423-0410.1985.tb00167.x.
de Silva, M., Contreras, M., & Mollison, P. L. (1985). Failure of passively administered anti-Rh to prevent secondary Rh responses. Vox sanguinis, 48(3), 178-80. https://doi.org/10.1111/j.1423-0410.1985.tb00167.x
de Silva, M, et al. "Failure of passively administered anti-Rh to prevent secondary Rh responses." Vox sanguinis vol. 48,3 (1985): 178-80. doi: https://doi.org/10.1111/j.1423-0410.1985.tb00167.x
de Silva M, Contreras M, Mollison PL. Failure of passively administered anti-Rh to prevent secondary Rh responses. Vox Sang. 1985;48(3):178-80. doi: 10.1111/j.1423-0410.1985.tb00167.x. PMID: 2984846.
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Vox Sang. 1985;48(3):178-80. doi: 10.1111/j.1423-0410.1985.tb00167.x.

Failure of passively administered anti-Rh to prevent secondary Rh responses.

Vox sanguinis

M de Silva, M Contreras, P L Mollison

PMID: 2984846 DOI: 10.1111/j.1423-0410.1985.tb00167.x

Abstract

Rh-negative women, immunized to Rh by previous pregnancies, with only low concentrations of IgG anti-Rh(D) in their plasma were assigned at random to test and control groups (7 subjects in each group). Both groups were challenged with an intravenous injection of 0.28 ml of Rh-positive red cells; in addition, the test group received 500 micrograms anti-Rh intramuscularly. 2 weeks after the injections, all subjects showed an increase in plasma anti-Rh concentration; levels in test and control groups were similar. It is concluded that in Rh-immunized subjects with low levels of IgG anti-Rh a secondary response to Rh cannot be prevented by giving passively administered anti-Rh with the red cells.

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