Mayo Clin Proc Innov Qual Outcomes. 2019 Oct 22;3(4):409-417. doi: 10.1016/j.mayocpiqo.2019.08.006. eCollection 2019 Dec.
Impact of Body Mass Index on the Association of Ankle-Brachial Index With All-Cause and Cardiovascular Mortality: Results from the National Health and Nutrition Examination Survey.
Mayo Clinic proceedings. Innovations, quality & outcomes
Mohammad-Ali Jazayeri, Salman Waheed, Zubair Shah, Deepak Parashara, Kamal Gupta
Affiliations
Affiliations
- Department of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS.
- Division of Cardiovascular Disease, University of Alabama Birmingham, AL.
- Division of Cardiovascular Disease, Kansas City Veterans Affairs Medical Center, MO.
PMID: 31993559
PMCID: PMC6978603 DOI: 10.1016/j.mayocpiqo.2019.08.006
Abstract
OBJECTIVE: To assess the influence of body-mass index (BMI) on the association of ankle-brachial index (ABI) with mortality.
PATIENTS AND METHODS: We conducted a prospective study of National Health and Nutrition Examination Survey participants enrolled from January 1, 1999 to December 31, 2002 with BMI and ABI data available. ABI categories were <0.9 (low), 0.9 to 1.3 (reference), and >1.3 (high). BMI categories were <30 kg/m
RESULTS: In total, 4614 subjects were included, with mean age 56±12 years and BMI 28±6 kg/m
CONCLUSION: In a US cohort, weight influenced the prognostic significance of high ABI. This may be related to technical factors reducing compressibility of the calf arteries in obese persons compared with those who are nonobese.
© 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc.
Keywords: ABI, ankle-brachial index; BMI, body mass index; BP, blood pressure; CV, cardiovascular; LE, lower extremity; MAC, medial arterial calcification; NHANES, National Health and Nutrition Examination Survey
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